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Dickins, B.J.A. 
ORCID: 0000-0002-0866-6232 and Kelsey, G.,
2008.
Evolution of imprinting: imprinted gene function in human disease [online encyclopaedia contribution].
In:
eLS [Encyclopedia of life sciences].
Chichester: John Wiley and Sons Ltd..
ISBN 9780470015902
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213765_8431%20Dickins%20Postprint.pdf - Post-print Download (119kB) | Preview |
Abstract
A subset of genes in mammals, known as imprinted genes, show a conditional expression strategy in which transcription depends on an allele’s parental origin. Several explanations have been advanced to explain this phenomenon and these, with varying levels of success, predict the functions of imprinted genes. After outlining these explanations, we summarize what is known about human genetic disorders involving abnormal expression of imprinted genes and ask what this can tell us about the evolution of imprinting.
| Item Type: | Book contribution | ||||
|---|---|---|---|---|---|
| Description: | Online encyclopaedia contribution. | ||||
| Creators: | Dickins, B.J.A. and Kelsey, G. | ||||
| Publisher: | John Wiley and Sons Ltd. | ||||
| Place of Publication: | Chichester | ||||
| Date: | 2008 | ||||
| ISBN: | 9780470015902 | ||||
| Identifiers: |
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| Divisions: | Schools > School of Science and Technology | ||||
| Record created by: | EPrints Services | ||||
| Date Added: | 09 Oct 2015 10:32 | ||||
| Last Modified: | 09 Jun 2017 13:32 | ||||
| URI: | https://irep.ntu.ac.uk/id/eprint/14359 |
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