Pulse mode operation of Love wave devices for biosensing applications

NEWTON, M.I., MCHALE, G., MARTIN, F., GIZELI, E. and MELZAK, K.A., 2001. Pulse mode operation of Love wave devices for biosensing applications. Analyst, 126 (12), pp. 2107-2109. ISSN 0003-2654

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Abstract

In this work we present a novel pulse mode Love wave biosensor that monitors both changes in amplitude and phase. A series of concentrations of 3350 molecular weight poly(ethylene glycol) (PEG) solutions are used as a calibration sequence for the pulse mode system using a network analyzer and high frequency oscilloscope. The operation of the pulse mode system is then compared to the continuous wave network analyzer by showing a sequence of deposition and removal of a model mass layer of palmitoyl-oleoyl-sn-glycerophosphocholine (POPC) vesicles. This experimental apparatus has the potential for making many hundreds of measurements a minute and so allowing the dynamics of fast interactions to be observed.

Item Type: Journal article
Publication Title: Analyst
Creators: Newton, M.I., McHale, G., Martin, F., Gizeli, E. and Melzak, K.A.
Publisher: Royal Society of Chemistry
Place of Publication: Cambridge
Date: 2001
Volume: 126
Number: 12
ISSN: 0003-2654
Divisions: Schools > School of Science and Technology
Depositing User: EPrints Services
Date Added: 09 Oct 2015 10:35
Last Modified: 19 Oct 2015 14:34
URI: http://irep.ntu.ac.uk/id/eprint/15290

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