Pulse mode operation of Love wave devices for biosensing applications

Newton, MI ORCID: 0000-0003-4231-1002, McHale, G, Martin, F, Gizeli, E and Melzak, KA, 2001. Pulse mode operation of Love wave devices for biosensing applications. Analyst, 126 (12), pp. 2107-2109. ISSN 0003-2654

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In this work we present a novel pulse mode Love wave biosensor that monitors both changes in amplitude and phase. A series of concentrations of 3350 molecular weight poly(ethylene glycol) (PEG) solutions are used as a calibration sequence for the pulse mode system using a network analyzer and high frequency oscilloscope. The operation of the pulse mode system is then compared to the continuous wave network analyzer by showing a sequence of deposition and removal of a model mass layer of palmitoyl-oleoyl-sn-glycerophosphocholine (POPC) vesicles. This experimental apparatus has the potential for making many hundreds of measurements a minute and so allowing the dynamics of fast interactions to be observed.

Item Type: Journal article
Publication Title: Analyst
Creators: Newton, M.I., McHale, G., Martin, F., Gizeli, E. and Melzak, K.A.
Publisher: Royal Society of Chemistry
Place of Publication: Cambridge
Date: 2001
Volume: 126
Number: 12
ISSN: 0003-2654
Divisions: Schools > School of Science and Technology
Depositing User: EPrints Services
Date Added: 09 Oct 2015 10:35
Last Modified: 09 Jun 2017 13:34
URI: http://irep.ntu.ac.uk/id/eprint/15290

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