Effect of fasting versus feeding on the bone metabolic response to running

Scott, J.P.R., Sale, C. ORCID: 0000-0002-5816-4169, Greeves, J.P., Casey, A., Dutton, J. and Fraser, W.D., 2012. Effect of fasting versus feeding on the bone metabolic response to running. Bone, 51 (6), pp. 990-999. ISSN 8756-3282

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Abstract

Individuals often perform exercise in the fasted state, but the effects on bone metabolism are not currently known. We compared the effect of an overnight fast with feeding a mixed meal on the bone metabolic response to treadmill running. Ten, physically-active males aged 28 ± 4 y (mean ± 1SD) completed two, counterbalanced, 8 d trials. After 3 d on a standardised diet, participants performed 60 min of treadmill running at 65% V02max on Day 4 following an overnight fast (FAST) or a standardised breakfast (FED). Blood samples were collected at baseline, before and during exercise, for 3h after exercise, and on four consecutive follow-up days (FU1-FU4). Plasma/serum were analysed for the c-terminal telopeptide region of collagen type 1 (P-CTX), n-terminal propeptides of procollagen type 1 (P1NP), osteocalcin (OC), bone alkaline phosphatase (bone ALP), parathyroid hormone (PTH), albumin-adjusted calcium, phosphate, osteoprotegerin (OPG), Cortisol, leptin and ghrelin.

Item Type:	Journal article
Publication Title:	Bone
Creators:	Scott, J.P.R., Sale, C., Greeves, J.P., Casey, A., Dutton, J. and Fraser, W.D.
Publisher:	Elsevier
Date:	2012
Volume:	51
Number:	6
ISSN:	8756-3282
Identifiers:	Number Type 10.1016/j.bone.2012.08.128 DOI
Divisions:	Schools > School of Science and Technology
Record created by:	EPrints Services
Date Added:	09 Oct 2015 11:02
Last Modified:	09 Jun 2017 13:47
URI:	https://irep.ntu.ac.uk/id/eprint/21901

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