CD40 ligand inhibits endothelial cell migration by increasing production of endothelial reactive oxygen species

Urbich, C., Dernbach, E., Aicher, A., Zeiher, A.M. and Dimmeler, S., 2002. CD40 ligand inhibits endothelial cell migration by increasing production of endothelial reactive oxygen species. Circulation, 106 (8), pp. 981-986. ISSN 0009-7322

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Abstract

Background— The CD40/CD40 ligand system is involved in atherogenesis. Activated T lymphocytes and platelets, which express high amounts of CD40 ligand (CD40L) on their surface, contribute significantly to plaque instability with ensuing thrombus formation, leading to acute coronary syndromes. Because reendothelialization may play a pivotal role for plaque stabilization, we investigated a potential role of CD40L on endothelial cell (EC) migration.

Item Type: Journal article
Publication Title: Circulation
Creators: Urbich, C., Dernbach, E., Aicher, A., Zeiher, A.M. and Dimmeler, S.
Publisher: American Heart Association
Place of Publication: Dallas, Texas, USA
Date: 2002
Volume: 106
Number: 8
ISSN: 0009-7322
Rights: Copyright © 2002 American Heart Association, Inc. All rights reserved. Unauthorized use prohibited
Divisions: Schools > School of Science and Technology
Depositing User: EPrints Services
Date Added: 09 Oct 2015 11:13
Last Modified: 19 Oct 2015 14:43
URI: http://irep.ntu.ac.uk/id/eprint/24537

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