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Santos, L.J. 
ORCID: 0000-0002-1915-6780, Reis, R.L. and Gomes, M.E.,
2015.
Harnessing magnetic-mechano actuation in regenerative medicine and tissue engineering.
Trends in Biotechnology, 33 (8), pp. 471-479.
ISSN 0167-7799
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Abstract
Mechanical stimulus is of upmost importance in tissues
developmental and regeneration processes as well as in
maintaining body homeostasis. Classical physiological
reactions encompass an increase of blood vessel diameter
upon exposure to high blood pressure, or the expansion
of cortical bone after continuous high-impact exercise. At a cellular level, it is well established that extracellular stiffness, topography, and remote magnetic actuation are instructive mechanical signals for stem cell differentiation. Based on this, biomaterials and their
properties can be designed to act as true stem cell
regulators, eventually leading to important advances in conventional tissue engineering techniques. This review
identifies the latest advances and tremendous potential of magnetic actuation within the scope of regenerative medicine and tissue engineering.
| Item Type: | Journal article | ||||||
|---|---|---|---|---|---|---|---|
| Publication Title: | Trends in Biotechnology | ||||||
| Creators: | Santos, L.J., Reis, R.L. and Gomes, M.E. | ||||||
| Publisher: | Elsevier | ||||||
| Date: | August 2015 | ||||||
| Volume: | 33 | ||||||
| Number: | 8 | ||||||
| ISSN: | 0167-7799 | ||||||
| Identifiers: |
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| Divisions: | Schools > School of Science and Technology | ||||||
| Record created by: | Jonathan Gallacher | ||||||
| Date Added: | 11 Jan 2017 11:00 | ||||||
| Last Modified: | 26 Jun 2017 03:00 | ||||||
| URI: | https://irep.ntu.ac.uk/id/eprint/29639 |
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