Enhancing the measurement of clinical outcomes using Microsoft Kinect

Breedon, P ORCID: https://orcid.org/0000-0002-1006-0942, Byrom, B, Siena, L ORCID: https://orcid.org/0000-0002-6908-7365 and Muehlhausen, W, 2016. Enhancing the measurement of clinical outcomes using Microsoft Kinect. In: Proceedings of the 2016 International Conference on Interactive Technologies and Games: EduRob in conjunction with iTAG 2016: iTAG 2016, Nottingham, 26-27 October 2016. Los Alamitos, CA: Institute of Electrical and Electronics Engineers, pp. 61-69. ISBN 9781509037384

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Abstract

There is a growing body of applications leveraging Microsoft Kinect and the associated Windows Software Development Kit in health and wellness. In particular, this platform has been valuable in developing interactive solutions for rehabilitation including creating more engaging exercise regimens and ensuring that exercises are performed correctly for optimal outcomes.
Clinical trials rely upon robust and validated methodologies to measure health status and to detect treatment-related changes over time to enable the efficacy and safety of new drug treatments to be assessed and measured. In many therapeutic areas, traditional outcome measures rely on subjective investigator and patient ratings. Subjective ratings are not always sensitive to detecting small improvements, are subject to inter- and intra-rater variability and limited in their ability to record detailed or subtle aspects of movement and mobility. For these reasons, objective measurements may provide greater sensitivity to detect treatment-related changes where they exist.
In this review paper, we explore the use of the Kinect platform to develop low-cost approaches to objectively measure aspects of movement. We consider published applications that measure aspects of gait and balance, upper extremity movement, chest wall motion and facial analysis. In each case, we explore the utility of the approach for clinical trials, and the precision and accuracy of estimates derived from the Kinect output.
We conclude that the use of games platforms such as Microsoft Kinect to measure clinical outcomes offer a versatile, easy to use and low-cost approach that may add significant value and utility to clinical drug development, in particular in replacing conventional subjective measures and providing richer information about movement than previously possible in large scale clinical trials, especially in the measurement of gross spatial movements. Regulatory acceptance of clinical outcomes collected in this way will be subject to comprehensive assessment of validity and clinical relevance, and this will require good quality peer-reviewed publications of scientific evidence.

Item Type:	Chapter in book
Creators:	Breedon, P., Byrom, B., Siena, L. and Muehlhausen, W.
Publisher:	Institute of Electrical and Electronics Engineers
Place of Publication:	Los Alamitos, CA
Date:	15 December 2016
ISBN:	9781509037384
Identifiers:	Number Type 10.1109/iTAG.2016.17 DOI
Divisions:	Schools > School of Architecture, Design and the Built Environment
Record created by:	Linda Sullivan
Date Added:	19 Jan 2017 16:30
Last Modified:	09 Jan 2018 09:36
URI:	https://irep.ntu.ac.uk/id/eprint/29878

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