The effect of postexercise carbohydrate and protein ingestion on bone metabolism

Tools

Townsend, R., Elliott-Sale, K.J. ORCID: 0000-0003-1122-5099, Currell, K., Tang, J., Fraser, W.D. and Sale, C. ORCID: 0000-0002-5816-4169, 2017. The effect of postexercise carbohydrate and protein ingestion on bone metabolism. Medicine & Science in Sports & Exercise, 49 (6), pp. 1209-1218. ISSN 0195-9131

Preview

Text
PubSub7551_Sale.pdf - Post-print
Download (693kB) | Preview

Official URL: http://doi.org/10.1249/MSS.0000000000001211

Abstract

Purpose
To investigate the effect of feeding carbohydrate and protein (CHO+PRO), immediately or 2 h after an exhaustive run, on the bone turnover response in endurance runners.
Methods
10 men (age 28±5 y, height 1.74±0.05 m, body mass 69.7±6.3 kg) performed treadmill running at 75%VO2max, until exhaustion, on three occasions. Blood was collected before and immediately, 1, 2, 3, 4 and 24 h post-exercise, for measurement of β-CTX, P1NP, PTH, PO4, ACa and Ca2+. This was a randomised, counterbalanced, placebo-controlled, single-blinded, cross-over study. The three trials were; i) placebo (PLA), PLA solution was ingested immediately and 2 h post-exercise, ii) immediate feeding (IF), CHO+PRO (1.5 g.kgBM-1 dextrose and 0.5 g.kgBM-1 whey) were ingested immediately post-exercise and PLA 2 h post-exercise, and iii) delayed feeding (DF), PLA was ingested immediately post-exercise and CHO+PRO solution 2 h post-exercise. Data were analysed using repeated measures ANOVA and post-hoc Tukey’s HSD.
Results
At 1 and 2 h post-exercise, β-CTX concentrations were lower in the IF trial than the DF and PLA trials (P≤0.001). At 3 h post-exercise, β-CTX concentrations were higher in the PLA trial than the IF (P≤0.001) and DF trials (P=0.026). At 4 h post-exercise, β-CTX concentrations were lower in the DF trial than the IF (P=0.003) and PLA trials (P≤0.001). At 4 h post-exercise, P1NP was higher in the IF trial than in DF (P=0.026) and PLA trials (P=0.001). At 3 h post-exercise, PTH was higher in the IF trial than the DF trial (P≤0.001).
Conclusions
Following exhaustive running, immediate ingestion of CHO+PRO may be beneficial, as it decreases bone resorption marker concentrations and increases bone formation marker concentrations; creating a more positive bone turnover balance.

Item Type:

Journal article

Publication Title:

Medicine & Science in Sports & Exercise

Creators:

Townsend, R., Elliott-Sale, K.J., Currell, K., Tang, J., Fraser, W.D. and Sale, C.

Publisher:

Lippincott Williams & Wilkins

Date:

1 June 2017

Volume:

Number: