Discovery of novel alphacoronaviruses in European rodents and shrews

Tsoleridis, T., Onianwa, O., Horncastle, E., Dayman, E., Zhu, M., Danjittrong, T., Wachtl, M., Behnke, J., Chapman, S., Strong, V. ORCID: 0000-0003-1348-1256, Dobbs, P., Ball, J., Tarlinton, R. and McClure, C., 2016. Discovery of novel alphacoronaviruses in European rodents and shrews. Viruses, 8 (3): 84. ISSN 1999-4915

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Abstract

Eight hundred and thirteen European rodents and shrews encompassing seven different species were screened for alphacoronaviruses using PCR detection. Novel alphacoronaviruses were detected in the species Rattus norvegicus, Microtus agrestis, Sorex araneus and Myodes glareolus. These, together with the recently described Lucheng virus found in China, form a distinct rodent/shrew-specific clade within the coronavirus phylogeny. Across a highly conserved region of the viral polymerase gene, the new members of this clade were up to 22% dissimilar at the nucleotide level to the previously described Lucheng virus. As such they might represent distinct species of alphacoronaviruses. These data greatly extend our knowledge of wildlife reservoirs of alphacoronaviruses.

Item Type: Journal article
Publication Title: Viruses
Creators: Tsoleridis, T., Onianwa, O., Horncastle, E., Dayman, E., Zhu, M., Danjittrong, T., Wachtl, M., Behnke, J., Chapman, S., Strong, V., Dobbs, P., Ball, J., Tarlinton, R. and McClure, C.
Publisher: MDPI
Date: 2016
Volume: 8
Number: 3
ISSN: 1999-4915
Identifiers:
NumberType
10.3390/v8030084DOI
v8030084Publisher Item Identifier
Divisions: Schools > School of Animal, Rural and Environmental Sciences
Depositing User: Jonathan Gallacher
Date Added: 04 May 2018 15:12
Last Modified: 04 May 2018 15:12
URI: http://irep.ntu.ac.uk/id/eprint/33448

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