Multimodal imaging of brain connectivity reveals predictors of individual decision strategy in statistical learning

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Karlaftis, V.M., Giorgio, J., Vértes, P.E., Wang, R., Shen, Y. ORCID: 0000-0002-2697-4239, Tino, P., Welchman, A. and Kourtzi, Z., 2019. Multimodal imaging of brain connectivity reveals predictors of individual decision strategy in statistical learning. Nature Human Behaviour, 3 (3), pp. 297-307. ISSN 2397-3374

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Official URL: https://doi.org/10.1038/s41562-018-0503-4

Abstract

Successful human behavior depends on the brain's ability to extract meaningful structure from information streams and make predictions about future events. Individuals can differ markedly in the decision strategies they use to learn the environment's statistics, yet we have little idea why. Here, we investigate whether the brain networks involved in learning temporal sequences without explicit reward differ depending on the decision strategy that individuals adopt. We demonstrate that individuals alter their decision strategy in response to changes in temporal statistics and engage dissociable circuits: extracting the exact sequence statistics relates to plasticity in motor cortico-striatal circuits, while selecting the most probable outcomes relates to plasticity in visual, motivational and executive cortico-striatal circuits. Combining graph metrics of functional and structural connectivity, we provide evidence that learning-dependent changes in these circuits predict individual decision strategy. Our findings propose brain plasticity mechanisms that mediate individual ability for interpreting the structure of variable environments.

Item Type:

Journal article

Publication Title:

Nature Human Behaviour

Creators:

Karlaftis, V.M., Giorgio, J., Vértes, P.E., Wang, R., Shen, Y., Tino, P., Welchman, A. and Kourtzi, Z.

Publisher:

Nature Publishing Group

Date:

2019

Volume:

Number: