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Hiramatsu, C., Paukner, A. 
ORCID: 0000-0002-3421-1864, Kuroshima, H., Fujita, K., Suomi, S.J. and Inoue-Murayama, M.,
2017.
Short poly-glutamine repeat in the androgen receptor in New World monkeys.
Meta Gene, 14, pp. 105-113.
ISSN 2214-5400
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Abstract
The androgen receptor mediates various physiological and developmental functions and is highly conserved in mammals. Although great intraspecific length polymorphisms in poly glutamine (poly-Q) and poly glycine (poly-G) regions of the androgen receptor in humans, apes and several Old World monkeys have been reported, little is known about the characteristics of these regions in New World monkeys. In this study, we surveyed 17 species of New World monkeys and found length polymorphisms in these regions in three species (common squirrel monkeys, tufted capuchin monkeys and owl monkeys). We found that the poly-Q region in New World monkeys is relatively shorter than that in catarrhines (humans, apes and Old World monkeys). In addition, we observed that codon usage for poly-G region in New World monkeys is unique among primates. These results suggest that the length of polymorphic regions in androgen receptor genes have evolved uniquely in New World monkeys.
| Item Type: | Journal article | ||||||
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| Publication Title: | Meta Gene | ||||||
| Creators: | Hiramatsu, C., Paukner, A., Kuroshima, H., Fujita, K., Suomi, S.J. and Inoue-Murayama, M. | ||||||
| Publisher: | Elsevier | ||||||
| Date: | 2017 | ||||||
| Volume: | 14 | ||||||
| ISSN: | 2214-5400 | ||||||
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| Divisions: | Schools > School of Social Sciences | ||||||
| Record created by: | Jonathan Gallacher | ||||||
| Date Added: | 25 Jan 2019 13:45 | ||||||
| Last Modified: | 29 Mar 2019 09:38 | ||||||
| URI: | https://irep.ntu.ac.uk/id/eprint/35689 |
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