Hybrids of polymeric capsules, lipids, and nanoparticles: thermodynamics and temperature rise at the nanoscale and emerging applications

Parakhonskiy, B.V., Parak, W.J., Volodkin, D. ORCID: 0000-0001-7474-5329 and Skirtach, A.G., 2019. Hybrids of polymeric capsules, lipids, and nanoparticles: thermodynamics and temperature rise at the nanoscale and emerging applications. Langmuir, 35 (26), pp. 8574-8583. ISSN 0743-7463

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Abstract

The importance of thermodynamics does not need to be emphasized. Indeed, elevated temperature processes govern not only industrial scale production, but also self-assembly, chemical reaction, interaction between molecules, etc. Not surprisingly, biological processes take typically place at defined temperature. Here, we look at possibilities to raise the localized temperature by a laser around noble metal nanoparticles incorporated into shells of layer-bylayer (LbL) polyelectrolyte microcapsules – freely suspended delivery vehicles in aqueous solution, developed in the Department of Interfaces, Max-Planck Institute of Colloids and Interfaces headed by Helmuth Möhwald. Understanding the mechanisms around localized temperature rise is essential, that is why we analyze thermodynamics at the nanoscale, the influence of incident intensity, nanoparticle size, their distribution and aggregation state. This leads us to scrutinize "global" (used for thermal encapsulation) versus "local" (used for release of encapsulated materials) temperature around nanoparticles. Similar analysis is extended to the lipid membrane system of vesicles and cells, on which nanoparticles are adsorbed. Insights are provided into the mechanisms of physico-chemical and biological effects, the nature of which has always been profoundly, interactively, and engagingly discussed in the Department. This analysis is combined with recent developments providing outlook and highlighting a broad range of emerging applications.

Item Type:	Journal article
Publication Title:	Langmuir
Creators:	Parakhonskiy, B.V., Parak, W.J., Volodkin, D. and Skirtach, A.G.
Publisher:	American Chemical Society
Date:	2019
Volume:	35
Number:	26
ISSN:	0743-7463
Identifiers:	Number Type 10.1021/acs.langmuir.8b04331 DOI
Divisions:	Schools > School of Science and Technology
Record created by:	Linda Sullivan
Date Added:	06 Jun 2019 08:57
Last Modified:	09 Apr 2020 03:38
URI:	https://irep.ntu.ac.uk/id/eprint/36714

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