Bacterial imprinting at Pickering emulsion interfaces

Shen, X., Svensson Bonde, J., Kamra, T., Bülow, L., Leo, J.C. ORCID: 0000-0002-7066-7527, Linke, D. and Ye, L., 2014. Bacterial imprinting at Pickering emulsion interfaces. Angewandte Chemie International Edition, 53 (40), pp. 10687-10690. ISSN 1433-7851

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Abstract

We demonstrate that the tendency of bacteria to assemble at oil-water interface can be utilized to create microbial recognition sites on the surface of polymer beads. In this work, two different groups of bacteria were first treated with acryloyl-functionalized chitosan, and then used to stabilize an oil-in-water emulsion composed of crosslinking monomer dispersed in aqueous buffer. Polymerization of the oil phase followed by removal of the bacterial template resulted in well-defined polymer beads bearing bacterial imprints. Chemical passivation of chitosan and cell displacement assays indicate that the bacterial recognition on the polymer beads was dependent on the nature of the pre-polymer and the target bacteria. The functional materials for microbial recognition show great potential for constructing cell-cell communication networks, biosensors, and new platforms for testing antibiotic drugs.

Item Type:	Journal article
Publication Title:	Angewandte Chemie International Edition
Creators:	Shen, X., Svensson Bonde, J., Kamra, T., Bülow, L., Leo, J.C., Linke, D. and Ye, L.
Publisher:	Wiley-VCH Verlag GmbH & Co. on behalf of the German Chemical Society
Date:	26 September 2014
Volume:	53
Number:	40
ISSN:	1433-7851
Identifiers:	Number Type 10.1002/anie.201406049 DOI
Divisions:	Schools > School of Science and Technology
Record created by:	Jill Tomkinson
Date Added:	19 Jun 2019 13:11
Last Modified:	25 Jun 2019 13:09
URI:	https://irep.ntu.ac.uk/id/eprint/36862

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