The effects of inspiratory muscle training in older adults

MILLS, D.E., JOHNSON, M.A., BARNETT, Y.A., SMITH, W.H.T. and SHARPE, G.R., 2015. The effects of inspiratory muscle training in older adults. Medicine & Science in Sports & Exercise, 47 (4), pp. 691-697. ISSN 0195-9131

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Abstract

Purpose: Declining inspiratory muscle function and structure and systemic low-level inflammation and oxidative stress may contribute to morbidity and mortality during normal ageing. Therefore, we examined the effects of inspiratory muscle training (IMT) in older adults on inspiratory muscle function and structure and systemic inflammation and oxidative stress, and re-examined the reported positive effects of IMT on respiratory muscle strength, inspiratory muscle endurance, spirometry, exercise performance, physical activity levels (PAL) and quality of life (QoL). Methods: Thirty-four healthy older adults (68 ± 3 years) with normal spirometry, respiratory muscle strength and physical fitness were divided equally into a pressure-threshold IMT or sham-hypoxic placebo group. Before and after an 8 week intervention, measurements were taken for dynamic inspiratory muscle function and inspiratory muscle endurance using a weighted plunger pressure-threshold loading device, diaphragm thickness using B-mode ultrasonography, plasma cytokine concentrations using immunoassays, DNA damage levels in peripheral blood mononuclear cells (PBMC) using Comet Assays, spirometry, maximal mouth pressures, exercise performance using a six minute walk test, PAL using a questionnaire and accelerometry, and QoL using a questionnaire.

Item Type: Journal article
Publication Title: Medicine & Science in Sports & Exercise
Creators: Mills, D.E., Johnson, M.A., Barnett, Y.A., Smith, W.H.T. and Sharpe, G.R.
Publisher: Lippincott Williams & Wilkins for the American College of Sports Medicine
Place of Publication: Indianapolis, IN
Date: 2015
Volume: 47
Number: 4
ISSN: 0195-9131
Identifiers:
NumberType
10.1249/MSS.0000000000000474DOI
Rights: © 2015 American College of Sports Medicine
Divisions: Schools > School of Science and Technology
Depositing User: EPrints Services
Date Added: 09 Oct 2015 09:51
Last Modified: 23 Aug 2016 09:06
URI: http://irep.ntu.ac.uk/id/eprint/3924

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