Application of mesoporous silica nanoparticles as drug delivery carriers for chemotherapeutic agents

Alyassin, Y., Sayed, E.G., Mehta, P., Ruparelia, K., Arshad, M.S., Rasekh, M., Shepherd, J., Kucukdurgut, I., Wilson, P.B. ORCID: 0000-0003-0207-2246, Singh, N., Chang, M.-W., Fatouros, D.G. and Ahmad, Z., 2020. Application of mesoporous silica nanoparticles as drug delivery carriers for chemotherapeutic agents. Drug Discovery Today. ISSN 1359-6446

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Abstract

Recently, remarkable efforts have focused on research towards enhancing and delivering efficacious and advanced therapeutic agents. Even though this involves significant challenges, innovative techniques and materials have been explored to overcome these. The advantageous properties of mesoporous silica nanoparticles (MSNs), such as unique morphologies and geometries, makes then favorable for use for various drug delivery targeting purposes, particularly in cancer therapy. As we discuss here, MSNs have been utilized over the past few decades to improve the efficiency of anticancer drugs by enhancing their solubility to render them suitable for application, reducing adverse effects, and improving their anticancer cytotoxic efficiency.

Item Type: Journal article
Publication Title: Drug Discovery Today
Creators: Alyassin, Y., Sayed, E.G., Mehta, P., Ruparelia, K., Arshad, M.S., Rasekh, M., Shepherd, J., Kucukdurgut, I., Wilson, P.B., Singh, N., Chang, M.-W., Fatouros, D.G. and Ahmad, Z.
Publisher: Elsevier
Date: 16 June 2020
ISSN: 1359-6446
Identifiers:
NumberType
10.1016/j.drudis.2020.06.006DOI
S1359644620302312Publisher Item Identifier
1339684Other
Divisions: Schools > School of Animal, Rural and Environmental Sciences
Record created by: Linda Sullivan
Date Added: 30 Jun 2020 10:44
Last Modified: 15 Jul 2020 13:18
URI: http://irep.ntu.ac.uk/id/eprint/40139

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