Tools
Tools
Shirzad, M., Zolfagharian, A., Matbouei, A. and Bodaghi, M. 
ORCID: 0000-0002-0707-944X,
2021.
Design, evaluation, and optimization of 3D printed truss scaffolds for bone tissue engineering.
Journal of the Mechanical Behavior of Biomedical Materials: 104594.
ISSN 1751-6161
|
Text
1439153_Bodaghi.pdf - Post-print Download (2MB) | Preview |
Abstract
One of tissue engineering's main goals is to fabricate three-dimensional (3D) scaffolds with interconnected pores to reconstruct and regenerate damaged or deformed tissues and organs. In this regard, 3D printing is a promising technique for the fabrication of tissue scaffolds, which can precisely make predetermined and complicated architectures. This study aims to investigate and optimize the physical, mechanical, and biological properties of 3D truss architecture tissue scaffolds with different pore geometries. The mechanical properties of poly (methyl methacrylate) scaffolds are analysed experimentally and numerically. Furthermore, the mechanical and physical properties of scaffolds are optimized with response surface methodology (RSM), and cell adhesion of the 3D truss scaffold studies. Results demonstrate that mechanical properties of the simple and gradient scaffolds have different mechanical behaviors that are strongly correlated with pore size and their architectures, rather than merely the values of the porosity. It is also observed that the RSM technique can enable designers to enhance mechanical and physical properties of scaffolds at low cost. Moreover, the results of biological behaviour can endorse the reliability of 3D truss architecture in bone tissue engineering.
| Item Type: | Journal article | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Publication Title: | Journal of the Mechanical Behavior of Biomedical Materials | ||||||||
| Creators: | Shirzad, M., Zolfagharian, A., Matbouei, A. and Bodaghi, M. | ||||||||
| Publisher: | Elsevier | ||||||||
| Date: | 15 May 2021 | ||||||||
| ISSN: | 1751-6161 | ||||||||
| Identifiers: |
|
||||||||
| Divisions: | Schools > School of Science and Technology | ||||||||
| Record created by: | Jonathan Gallacher | ||||||||
| Date Added: | 19 May 2021 15:11 | ||||||||
| Last Modified: | 15 May 2022 03:00 | ||||||||
| URI: | https://irep.ntu.ac.uk/id/eprint/42889 |
Actions (login required)
 |
Edit View |
Views
Views per month over past year
Downloads
Downloads per month over past year
