The effect of β-alanine supplementation on high intensity cycling capacity in normoxia and hypoxia

Patel, K.A., Farias de Oliveira, L., Sale, C. ORCID: 0000-0002-5816-4169 and James, R.M. ORCID: 0000-0002-7119-3159, 2021. The effect of β-alanine supplementation on high intensity cycling capacity in normoxia and hypoxia. Journal of Sports Sciences, 39 (11), pp. 1295-1301. ISSN 0264-0414

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Abstract

The availability of dietary beta-alanine (BA) is the limiting factor in carnosine synthesis within human muscle due to its low intramuscular concentration and substrate affinity. Carnosine can accept hydrogen ions (H+), making it an important intramuscular buffer against exercise-induced acidosis. Metabolite accumulation rate increases when exercising in hypoxic conditions, thus an increased carnosine concentration could attenuate H+ build-up when exercising in hypoxic conditions. This study examined the effects of BA supplementation on high intensity cycling capacity in normoxia and hypoxia. In a double-blind design, nineteen males were matched into a BA group (n = 10; 6.4 g·d−1) or a placebo group (PLA; n = 9) and supplemented for 28 days, carrying out two pre- and two post-supplementation cycling capacity trials at 110% of powermax, one in normoxia and one in hypoxia (15.5% O2). Hypoxia led to a 9.1% reduction in exercise capacity, but BA supplementation had no significant effect on exercise capacity in normoxia or hypoxia (P > 0.05). Blood lactate accumulation showed a significant trial x time interaction post-supplementation (P = 0.016), although this was not significantly different between groups. BA supplementation did not increase high intensity cycling capacity in normoxia, nor did it improve cycling capacity in hypoxia even though exercise capacity was reduced under hypoxic conditions.

Item Type: Journal article
Publication Title: Journal of Sports Sciences
Creators: Patel, K.A., Farias de Oliveira, L., Sale, C. and James, R.M.
Publisher: Taylor & Francis
Date: 2021
Volume: 39
Number: 11
ISSN: 0264-0414
Identifiers:
NumberType
10.1080/02640414.2020.1867416DOI
1424806Other
Divisions: Schools > School of Science and Technology
Record created by: Linda Sullivan
Date Added: 07 Jun 2021 09:46
Last Modified: 07 Jun 2021 09:46
URI: http://irep.ntu.ac.uk/id/eprint/42991

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