Bioengineering approaches for delivering growth factors: a focus on bone and cartilage regeneration

Shakoor, S., Kibble, E. and El-Jawhari, J.J. ORCID: 0000-0002-0580-4492, 2022. Bioengineering approaches for delivering growth factors: a focus on bone and cartilage regeneration. Bioengineering, 9 (5): 223.

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Abstract

Growth factors are bio-factors that target reparatory cells during bone regeneration. These growth factors are needed in complicated conditions of bone and joint damage to enhance tissue repair. The delivery of these growth factors is key to ensuring the effectiveness of regenerative therapy. This review discusses the roles of various growth factors in bone and cartilage regeneration. The methods of delivery of natural or recombinant growth factors are reviewed. Different types of scaffolds, encapsulation, Layer-by-layer assembly, and hydrogels are tools for growth factor delivery. Considering the advantages and limitations of these methods is essential to developing regenerative therapies. Further research can accordingly be planned to have new or combined technologies serving this purpose.

Item Type: Journal article
Publication Title: Bioengineering
Creators: Shakoor, S., Kibble, E. and El-Jawhari, J.J.
Publisher: MDPI AG
Date: 2022
Volume: 9
Number: 5
Identifiers:
NumberType
10.3390/bioengineering9050223DOI
1573999Other
Rights: Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Divisions: Schools > School of Science and Technology
Record created by: Linda Sullivan
Date Added: 04 Aug 2022 08:25
Last Modified: 04 Aug 2022 08:25
URI: http://irep.ntu.ac.uk/id/eprint/46824

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