Early life exposure to PM 2.5 and sleep disturbances in preschoolers from 551 cities of China

Cai, J., Shen, Y., Zhao, Y., Meng, X., Niu, Y., Chen, R., Quan, G., Li, H., Groeger, J.A. ORCID: 0000-0002-3582-1058, Du, W. ORCID: 0000-0002-5115-7214, Hua, J. and Kan, H., 2022. Early life exposure to PM 2.5 and sleep disturbances in preschoolers from 551 cities of China. American Journal of Respiratory and Critical Care Medicine. ISSN 1073-449X

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Abstract

Rationale: Air pollution has been linked with sleep disturbance in adults, but the association in children remains unclear.

Objectives: To examine the associations of prenatal and postnatal exposure to fine particulate matter (PM2.5) with sleep quality and sleep disturbances among children in 551 Chinese cities.

Methods: A total of 115,023 children aged 3–7 years from the Chinese National Cohort of Motor Development were included. Sleep quality was measured using the Children’s Sleep Habits Questionnaire (CSHQ). PM2.5 exposure was estimated using a satellite-based model. Generalized additive mixed models with Gaussian and binomial distributions were used to examine the associations of PM2.5 exposure with CSHQ scores and risk of sleep disturbance, respectively, adjusting for demographic characteristics and temporal trends.

Measurements and Main Results: Early life PM2.5 exposure was associated with higher total CSHQ score, and the association was stronger for exposure in age 0–3 years (change of CSHQ score per interquartile range increase of PM2.5=0.46, 95% CI: 0.29, 0.63) than during pregnancy (0.22, 95% CI: 0.12, 0.32). The associations were more evident on sleep-disordered breathing and daytime sleepiness. Postnatal PM2.5 exposure was associated with increased risk of sleep disturbance (adjusted odds ratios for per interquartile range increase of PM2.5 exposure in age 0–3=1.10, 95% CI: 1.04, 1.15), but no associations were found for prenatal exposure. Children who were breastfed for less than 6 months and had NICU admission may be more vulnerable to sleep disturbance related to PM2.5 exposure.

Conclusions: PM2.5 exposure can impair sleep quality in preschool children.

Item Type: Journal article
Publication Title: American Journal of Respiratory and Critical Care Medicine
Creators: Cai, J., Shen, Y., Zhao, Y., Meng, X., Niu, Y., Chen, R., Quan, G., Li, H., Groeger, J.A., Du, W., Hua, J. and Kan, H.
Publisher: American Thoracic Society
Date: 28 September 2022
ISSN: 1073-449X
Identifiers:
NumberType
10.1164/rccm.202204-0740OCDOI
1606053Other
Divisions: Schools > School of Social Sciences
Record created by: Laura Ward
Date Added: 05 Oct 2022 08:26
Last Modified: 09 Nov 2022 14:01
URI: https://irep.ntu.ac.uk/id/eprint/47212

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