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Umar, T.P., Sayad, R., Mokresh, M.E., Chakhide, M., Mahjoub, R., Saad, H., Griffiths, M.D. 
ORCID: 0000-0001-8880-6524, Khair, K. and Mohammed, L.,
2023.
Health-related quality of life among adult patients with Ehlers-Danlos Syndrome: a systematic review and meta-analysis.
Mediterranean Journal of Clinical Psychology, 11 (2).
ISSN 2282-1619
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Abstract
Background: Ehlers-Danlos Syndrome (EDS) is a serious chronic condition that leads to diminished quality of life and psychological problems. The current study aimed to systematically reviewed the existing literature on EDS patients' health-related quality of life (HRQoL), calculate mean HRQoL value, and determine the association between demographical and publication-related characteristics with HRQoL.
Methods: Four electronic databases were used to identify papers on HRQOL in adults with EDS (Scopus, Medline (by Pubmed), Epistemonikos, and Web of Science). A random-effects meta-analysis was also performed on the 36-item Short Form Survey (SF-36) measure.
Results: We contained 37 studies that fulfilled the inclusion criteria. According to the SF-36 meta-analysis, EDS patients and the general population had significant differences in all HRQoL components (p<0.01). In EDS patients, the Physical Component Summary (35.34/100) was more seriously impacted than the Mental Component Summary (45.21/100) in these patients.
Conclusion: Individuals with EDS have significantly lower HRQoL in all aspects compared to the general population, with the physical component of wellbeing being the most pronounced disparity. Future research should look into the impact of different patient characteristics, evaluate the complications of EDS and their effects on wellbeing, and develop multiple intervention strategies to improve HRQoL.
| Item Type: | Journal article | ||||||
|---|---|---|---|---|---|---|---|
| Publication Title: | Mediterranean Journal of Clinical Psychology | ||||||
| Creators: | Umar, T.P., Sayad, R., Mokresh, M.E., Chakhide, M., Mahjoub, R., Saad, H., Griffiths, M.D., Khair, K. and Mohammed, L. | ||||||
| Publisher: | Universita degli Studi di Messina (University of Messina) | ||||||
| Date: | 2023 | ||||||
| Volume: | 11 | ||||||
| Number: | 2 | ||||||
| ISSN: | 2282-1619 | ||||||
| Identifiers: |
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| Rights: | ©2023 by the Author(s); licensee Mediterranean Journal of Clinical Psychology, Messina, Italy. This article is an open access article, licensed under a Creative Commons Attribution 4.0 Unported License (https://creativecommons.org/licenses/by/4.0/). | ||||||
| Divisions: | Schools > School of Social Sciences | ||||||
| Record created by: | Laura Ward | ||||||
| Date Added: | 04 Sep 2023 09:09 | ||||||
| Last Modified: | 04 Sep 2023 09:09 | ||||||
| URI: | https://irep.ntu.ac.uk/id/eprint/49641 |
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