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Negus, D. 
ORCID: 0000-0001-9047-4565, Foster, G. and Hoyles, L. ORCID: 0000-0002-6418-342X,
2023.
Lelliottia amnigena recovered from the lung of a harbour porpoise, and comparative analyses with Lelliottia spp.
Access Microbiology, 5 (11): 000694.v3.
ISSN 2516-8290
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Abstract
Strain M1325/93/1 (herein referred to by our laboratory identifier, GFKo1) of Lelliottia amnigena was isolated from the lung of a harbour porpoise in 1993. The genome sequence and antimicrobial resistance profile (genomic, phenotypic) of the strain were generated, with the genomic data compared with those from closely related bacteria. We demonstrate that the recently described chromosomally encoded AmpC β-lactamase bla LAQ is a core gene of L. amnigena , and suggest that new variants of this class of lactamase are encoded by other members of the genus Lelliottia . Although presence of bla LAQ is ubiquitous across the currently sequenced members of L. amnigena , we highlight that strain GFKo1 is sensitive to ampicillin and cephalosporins. These data suggest that bla LAQ may act as a useful genetic marker for identification of L. amnigena strains, but its presence may not correlate with expected phenotypic resistances. Further studies are required to determine the regulatory mechanisms of bla LAQ in L. amnigena .
| Item Type: | Journal article | ||||
|---|---|---|---|---|---|
| Publication Title: | Access Microbiology | ||||
| Creators: | Negus, D., Foster, G. and Hoyles, L. | ||||
| Publisher: | Microbiology Society | ||||
| Date: | November 2023 | ||||
| Volume: | 5 | ||||
| Number: | 11 | ||||
| ISSN: | 2516-8290 | ||||
| Identifiers: |
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| Rights: | ©Negus, Foster, Hoyles, 2023. The definitive peer reviewed, edited version of this article is published in Access Microbiology, 5(11), 2023, https://doi.org/10.1099/acmi.0.000694.v3 | ||||
| Divisions: | Schools > School of Science and Technology | ||||
| Record created by: | Jeremy Silvester | ||||
| Date Added: | 25 Oct 2023 10:03 | ||||
| Last Modified: | 29 Nov 2023 08:50 | ||||
| URI: | https://irep.ntu.ac.uk/id/eprint/50124 |
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