Change detection in children with autism: an auditory event-related fMRI study

Gomot, M, Bernard, FA, Davis, MH, Belmonte, MK ORCID: 0000-0002-4633-9400, Ashwin, C, Bullmore, ET and Baron-Cohen, S, 2006. Change detection in children with autism: an auditory event-related fMRI study. NeuroImage, 29 (2). ISSN 1053-8119


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Autism involves impairments in communication and social interaction, as well as high levels of repetitive, stereotypic and ritualistic behaviours, and extreme resistance to change. This latter dimension, whilst required for a diagnosis, has received less research attention. We hypothesise that this extreme resistance to change in autism is rooted in atypical processing of unexpected stimuli. We tested this using auditory event-related fMRI to determine regional brain activity associated with passive detection of infrequently occurring frequency-deviant and complex novel sounds in a no-task condition. Participants were twelve 10 to 15-year-old children with autism, and a group of 12 age- and sex-matched healthy controls.

Item Type: Journal article
Publication Title: NeuroImage
Creators: Gomot, M., Bernard, F.A., Davis, M.H., Belmonte, M.K., Ashwin, C., Bullmore, E.T. and Baron-Cohen, S.
Publisher: Elsevier
Place of Publication: The Netherlands
Date: 2006
Volume: 29
Number: 2
ISSN: 1053-8119
Divisions: Schools > School of Social Sciences
Depositing User: EPrints Services
Date Added: 09 Oct 2015 10:04
Last Modified: 09 Jun 2017 13:18

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