Change detection in children with autism: an auditory event-related fMRI study

GOMOT, M., BERNARD, F.A., DAVIS, M.H., BELMONTE, M.K., ASHWIN, C., BULLMORE, E.T. and BARON-COHEN, S., 2006. Change detection in children with autism: an auditory event-related fMRI study. NeuroImage, 29 (2). ISSN 1053-8119

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Abstract

Autism involves impairments in communication and social interaction, as well as high levels of repetitive, stereotypic and ritualistic behaviours, and extreme resistance to change. This latter dimension, whilst required for a diagnosis, has received less research attention. We hypothesise that this extreme resistance to change in autism is rooted in atypical processing of unexpected stimuli. We tested this using auditory event-related fMRI to determine regional brain activity associated with passive detection of infrequently occurring frequency-deviant and complex novel sounds in a no-task condition. Participants were twelve 10 to 15-year-old children with autism, and a group of 12 age- and sex-matched healthy controls.

Item Type: Journal article
Publication Title: NeuroImage
Creators: Gomot, M., Bernard, F.A., Davis, M.H., Belmonte, M.K., Ashwin, C., Bullmore, E.T. and Baron-Cohen, S.
Publisher: Elsevier
Place of Publication: The Netherlands
Date: 2006
Volume: 29
Number: 2
ISSN: 1053-8119
Identifiers:
NumberType
10.1016/j.neuroimage.2005.07.027DOI
Divisions: Schools > School of Social Sciences
Depositing User: EPrints Services
Date Added: 09 Oct 2015 10:04
Last Modified: 09 Jun 2017 13:18
URI: http://irep.ntu.ac.uk/id/eprint/7259

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