Triethylphosphite as a network forming agent enhances in-vitro biocompatibility and corrosion protection of hybrid organic-inorganic sol-gel coatings for Ti6Al4V alloys

EL HADAD, A.A.G., BARRANCO, V., JIMÉNEZ-MORALES, A., HICKMAN, G., GALVÁN, J. and PERRY, C.C., 2014. Triethylphosphite as a network forming agent enhances in-vitro biocompatibility and corrosion protection of hybrid organic-inorganic sol-gel coatings for Ti6Al4V alloys. Journal of Materials Chemistry B. ISSN 2050-750X

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Abstract

The biocompatibility and life of metallic implants can be enhanced through improving the biocompatibility and corrosion protection characteristics of the coatings used with these materials. In this study, triethylphosphite (TEP) was used to introduce phosphorus into organic-inorganic hybrid silica based sol gel coatings prepared using γ-methacryloxypropyltrimethoxysilane and tetramethylorthosilicate. Addition of TEP dramatically increased the rate of intermolecular condensation and resulted in materials showing greater cross linking. Protein (fibrinogen) uptake, osteoblast in vitro biocompatibility and corrosion resistance was enhanced in coatings containing TEP. Although higher concentrations of phosphorus supported the greatest improvement in biocompatibility, a compromise in the phosphorus concentration used would be required if corrosion resistance was most desirable parameter for optimisation. Films prepared by dip coating on Ti6Al4V alloys from these sols offer a promising alternative to wholly metallic prostheses.

Item Type: Journal article
Publication Title: Journal of Materials Chemistry B
Creators: El Hadad, A.A.G., Barranco, V., Jiménez-Morales, A., Hickman, G., Galván, J. and Perry, C.C.
Publisher: Royal Society of Chemistry
Date: 2014
ISSN: 2050-750X
Identifiers:
NumberType
10.1039/C4TB01175ADOI
Rights: © Royal Society of Chemistry 2014
Divisions: Schools > School of Science and Technology
Depositing User: EPrints Services
Date Added: 09 Oct 2015 10:08
Last Modified: 09 Jun 2017 13:19
URI: http://irep.ntu.ac.uk/id/eprint/8216

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