Current advances on the regeneration of musculoskeletal interfaces

Balestri, W, Morris, R ORCID: https://orcid.org/0000-0001-5511-3457, Hunt, J ORCID: https://orcid.org/0000-0002-5168-4778 and Reinwald, Y ORCID: https://orcid.org/0000-0001-6733-605X, 2021. Current advances on the regeneration of musculoskeletal interfaces. Tissue Engineering Part B: Reviews. ISSN 1937-3368

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Abstract

The regeneration of the musculoskeletal system has been widely investigated. There is now detailed knowledge about the organs composing this system. Research has also investigated the zones between individual tissues where physical, mechanical, and biochemical properties transition. However, the understanding of the regeneration of musculoskeletal interfaces is still lacking behind. Numerous disorders and injuries can degrade or damage tissue interfaces. Their inability to regenerate can delay the tissue repair and regeneration process, leading to graft instability, high morbidity, and pain. Moreover, the knowledge of the mechanism of tissue interface development is not complete. This review presents an overview of the most recent approaches of the regeneration of musculoskeletal interfaces, including the latest in vitro, preclinical, and clinical studies.

Item Type:	Journal article
Publication Title:	Tissue Engineering Part B: Reviews
Creators:	Balestri, W., Morris, R., Hunt, J. and Reinwald, Y.
Publisher:	Mary Ann Liebert
Date:	21 January 2021
ISSN:	1937-3368
Identifiers:	Number Type 10.1089/ten.teb.2020.0112 DOI 1395820 Other
Divisions:	Schools > School of Science and Technology
Record created by:	Jonathan Gallacher
Date Added:	11 Jan 2021 11:04
Last Modified:	21 Jan 2022 03:00
URI:	https://irep.ntu.ac.uk/id/eprint/41995

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