Items where Author is "Clader, JW"

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MCBRIAR, M.D., GUZIK, H., SHAPIRO, S., XU, R., PARUCHOVA, J., CLADER, J.W., O'NEILL, K., HAWES, B.E., SOROTA, S., MARGULIS, M., TUCKER, K., WESTON, D.J. and COX, K., 2006. Bicyclo[3.1.0]hexyl urea MCH-R1 melanin concentrating hormone (MCH) receptor-1 antagonists: impacting hERG liability via aryl modifications. Bioorganic & Medicinal Chemistry Letters, 16 (16), pp. 4262-4265. ISSN 0960-894X

XU, R., LI, S., PARUCHOVA, J., MCBRIAR, M.D., GUZIK, H., PALANI, A., CLADER, J.W., COX, K., GREENLEE, W.J., HAWES, B.E., KOWALSKI, T., O'NEILL, K., SPAR, B.D., WEIG, B. and WESTON, D.J., 2006. Bicyclo[4.1.0]heptanes as phenyl replacements for melanin concentrating hormone receptor antagonists. Bioorganic & Medicinal Chemistry, 14 (10), pp. 3285-3299. ISSN 0968-0896

MCBRIAR, M.D., GUZIK, H., SHAPIRO, S., PARUCHOVA, J., XU, R., PALANI, A., CLADER, J.W., COX, K., GREENLEE, W.J., HAWES, B.E., KOWALSKI, T., O'NEILL, K., SPAR, B.D., WEIG, B., WESTON, D.J., FARLEY, C. and COOK, J., 2006. Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of Bicyclo[3.1.0]hexyl ureas. Journal of Medical Chemistry, 49 (7), pp. 2294-2310. ISSN 0022-2633

MCBRIAR, M.D., XU, R., CLADER, J.W., HAWES, B.E., O'NEILL, K., WESTON, D.J. and COX, K., 2006. Regioisomeric bicyclo[3.1.0]hexyl urea MCH-R1 antagonists: addressing the fragmentation issues of bicyclohexyl ureas. In: 232nd ACS National Meeting, San Francisco, CA, USA, 10-14 September 2006, San Francisco, CA.

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