Verderio, E. ORCID: 0000-0001-9153-8997, Scarpellini, A. and Johnson, T., 2008. Novel interactions of transglutaminase-2 with heparan sulphate proteoglycans: reflection on physiological implications. Amino Acids, 36 (4), pp. 671-677.
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Abstract
This mini-review brings together information from publications and recent conference proceedings that have shed light on the biological interaction between transglutaminase-2 and heparan sulphate proteoglycans. We subsequently draw hypothesis of possible implications in the wound healing process. There is a substantial overlap in the action of transglutaminase-2 and the heparan sulphate proteoglycan syndecan-4 in normal and abnormal wound repair. Our latest findings have identified syndecan-4 as a possible binding and signalling partner of fibronectinbound TG2 and support the idea that transglutaminase-2 and syndecan-4 acts in synergy.
Item Type: | Journal article | ||||
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Description: | The original publication is available at www.springerlink.com. | ||||
Publication Title: | Amino Acids | ||||
Creators: | Verderio, E., Scarpellini, A. and Johnson, T. | ||||
Publisher: | Springer Verlag | ||||
Date: | 2008 | ||||
Volume: | 36 | ||||
Number: | 4 | ||||
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Rights: | © 2008 Springer, part of Springer Science+Business Media | ||||
Divisions: | Schools > School of Science and Technology | ||||
Record created by: | EPrints Services | ||||
Date Added: | 09 Oct 2015 10:25 | ||||
Last Modified: | 09 Jun 2017 13:29 | ||||
URI: | https://irep.ntu.ac.uk/id/eprint/12778 |
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