VERDERIO, E., SCARPELLINI, A. and JOHNSON, T., 2008. Novel interactions of transglutaminase-2 with heparan sulphate proteoglycans: reflection on physiological implications. Amino Acids, 36 (4), pp. 671-677.
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This mini-review brings together information from publications and recent conference proceedings that have shed light on the biological interaction between transglutaminase-2 and heparan sulphate proteoglycans. We subsequently draw hypothesis of possible implications in the wound healing process. There is a substantial overlap in the action of transglutaminase-2 and the heparan sulphate proteoglycan syndecan-4 in normal and abnormal wound repair. Our latest findings have identified syndecan-4 as a possible binding and signalling partner of fibronectinbound TG2 and support the idea that transglutaminase-2 and syndecan-4 acts in synergy.
|Item Type:||Journal article|
|Description:||The original publication is available at www.springerlink.com.|
|Publication Title:||Amino Acids|
|Creators:||Verderio, E., Scarpellini, A. and Johnson, T.|
|Rights:||© 2008 Springer, part of Springer Science+Business Media|
|Divisions:||Schools > School of Science and Technology|
|Depositing User:||EPrints Services|
|Date Added:||09 Oct 2015 10:25|
|Last Modified:||23 Aug 2016 09:09|
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