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Hemming, R.A., Bell, M., Duffy, L.J., Bristow, J., Wallis, J.D. 
ORCID: 0000-0001-7259-8783, Allin, S.M. ORCID: 0000-0001-5198-9339 and Bulman Page, P.C.,
2019.
A novel and highly stereoselective route for the synthesis of non-racemic 3-substituted isoindolin-1-one targets.
Tetrahedron, 75 (1), pp. 121-127.
ISSN 0040-4020
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Abstract
A new, versatile and highly stereoselective approach for the synthesis of non-racemic 3-substituted isoindolin-1-ones is described from a readily available chiral template. The potential of this new protocol is demonstrated through the synthesis of an enantiomerically enriched 3-alkyl N-H isoindolin-1-one target with an e.e. of 98%.
| Item Type: | Journal article | ||||||
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| Publication Title: | Tetrahedron | ||||||
| Creators: | Hemming, R.A., Bell, M., Duffy, L.J., Bristow, J., Wallis, J.D., Allin, S.M. and Bulman Page, P.C. | ||||||
| Publisher: | Elsevier | ||||||
| Date: | 3 January 2019 | ||||||
| Volume: | 75 | ||||||
| Number: | 1 | ||||||
| ISSN: | 0040-4020 | ||||||
| Identifiers: |
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| Divisions: | Schools > School of Science and Technology | ||||||
| Record created by: | Linda Sullivan | ||||||
| Date Added: | 18 Jul 2019 15:17 | ||||||
| Last Modified: | 31 May 2021 15:13 | ||||||
| URI: | https://irep.ntu.ac.uk/id/eprint/37120 |
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