Hyena palaeogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena

Westbury, M.V., Hartmann, S., Barlow, A. ORCID: 0000-0002-5532-9458, Preick, M., Ridush, B., Nagel, D., Rathgeber, T., Ziegler, R., Baryshnikov, G., Sheng, G., Ludwig, A., Wiesel, I., Dalen, L., Bibi, F., Werdelin, L., Heller, R. and Hofreiter, M., 2019. Hyena palaeogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena. Science Advances. ISSN 2375-2548 (Forthcoming)

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Abstract

The genus Crocuta (African spotted and Eurasian cave hyenas) includes several closely related extinct and extant lineages. The relationships among these lineages, ​ however, are contentious​. Through the generation of population level palaeogenomes from late Pleistocene Eurasian cave hyena and genomes from modern African spotted hyena, we reveal the cross-continental evolutionary relationships between these enigmatic hyena lineages. We find a deep divergence (~2.5 Ma) between African and Eurasian Crocuta populations, suggesting ancestral Crocuta left Africa around the same time as early​ Homo. Moreover, we find discordance between nuclear and mitochondrial phylogenies and evidence for bidirectional gene flow between African and Eurasian ​ Crocuta after the lineages split, which may have complicated prior taxonomic classifications. Finally, we find a number of introgressed loci that attained high frequencies within the recipient lineage, suggesting some level of adaptive advantage from admixture.

Item Type: Journal article
Alternative Title: Evolutionary genomics of Crocuta [short title]
Publication Title: Science Advances
Creators: Westbury, M.V., Hartmann, S., Barlow, A., Preick, M., Ridush, B., Nagel, D., Rathgeber, T., Ziegler, R., Baryshnikov, G., Sheng, G., Ludwig, A., Wiesel, I., Dalen, L., Bibi, F., Werdelin, L., Heller, R. and Hofreiter, M.
Publisher: American Association for the Advancement of Science
Date: 17 December 2019
ISSN: 2375-2548
Identifiers:
NumberType
1287503Other
Divisions: Schools > School of Science and Technology
Depositing User: Linda Sullivan
Date Added: 06 Feb 2020 10:50
Last Modified: 18 Feb 2020 12:30
URI: http://irep.ntu.ac.uk/id/eprint/39175

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