Hyena palaeogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena

Westbury, MV, Hartmann, S, Barlow, A ORCID: https://orcid.org/0000-0002-5532-9458, Preick, M, Ridush, B, Nagel, D, Rathgeber, T, Ziegler, R, Baryshnikov, G, Sheng, G, Ludwig, A, Wiesel, I, Dalen, L, Bibi, F, Werdelin, L, Heller, R and Hofreiter, M, 2020. Hyena palaeogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena. Science Advances, 6 (11): eaay0456. ISSN 2375-2548

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Abstract

The genus Crocuta (African spotted and Eurasian cave hyenas) includes several closely related extinct and extant lineages. The relationships among these lineages, ​ however, are contentious​. Through the generation of population level palaeogenomes from late Pleistocene Eurasian cave hyena and genomes from modern African spotted hyena, we reveal the cross-continental evolutionary relationships between these enigmatic hyena lineages. We find a deep divergence (~2.5 Ma) between African and Eurasian Crocuta populations, suggesting ancestral Crocuta left Africa around the same time as early​ Homo. Moreover, we find discordance between nuclear and mitochondrial phylogenies and evidence for bidirectional gene flow between African and Eurasian ​ Crocuta after the lineages split, which may have complicated prior taxonomic classifications. Finally, we find a number of introgressed loci that attained high frequencies within the recipient lineage, suggesting some level of adaptive advantage from admixture.

Item Type:	Journal article
Alternative Title:	Evolutionary genomics of Crocuta [short title]
Publication Title:	Science Advances
Creators:	Westbury, M.V., Hartmann, S., Barlow, A., Preick, M., Ridush, B., Nagel, D., Rathgeber, T., Ziegler, R., Baryshnikov, G., Sheng, G., Ludwig, A., Wiesel, I., Dalen, L., Bibi, F., Werdelin, L., Heller, R. and Hofreiter, M.
Publisher:	American Association for the Advancement of Science
Date:	13 March 2020
Volume:	6
Number:	11
ISSN:	2375-2548
Identifiers:	Number Type 10.1126/sciadv.aay0456 DOI 1287503 Other
Divisions:	Schools > School of Science and Technology
Record created by:	Linda Sullivan
Date Added:	06 Feb 2020 10:50
Last Modified:	21 Jan 2021 11:58
URI:	https://irep.ntu.ac.uk/id/eprint/39175

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