Tools
Tools
O'Hare, L. 
ORCID: 0000-0003-0331-3646, Goodwin, P. ORCID: 0000-0002-1396-2626, Sharp, A., Contillo, A. and Pavan, A.,
2021.
Improvement in visual perception after high-frequency transcranial random noise stimulation (hf-tRNS) in those with migraine: an equivalent noise approach.
Neuropsychologia, 161: 107990.
ISSN 0028-3932
|
Text
1460133_O'Hare.pdf - Post-print Download (572kB) | Preview |
Abstract
Migraine is a common neurological disorder with strong links to vision. Interictal migraine is thought to be characterised by internal noise in the brain, possibly due to increased variability in neural firing, which can be estimated using equivalent noise tasks. High-frequency transcranial random noise stimulation (hf-tRNS) can be used to modulate levels of internal noise in the brain, and so presents a possible therapy to redress noise levels in the migraine brain. This is a case-control study using a 2-alternative forced choice (2AFC) design. hf-tRNS and Sham control stimulation were used alongside a global motion direction discrimination task and visually based equivalent noise tasks. The migraine group demonstrated increased baseline internal noise levels compared to the control group. Internal noise levels, and sampling, were reduced using hf-tRNS but not Sham stimulation. However, there were no differences in terms of coherence thresholds, slopes, and lapse rate for global motion discrimination between the two groups. This is the first demonstration of the possibility of decreasing internal noise levels in migraine using hf-tRNS. Future work could explore the possibility of neurostimulation as a therapy for migraine.
| Item Type: | Journal article | ||||||
|---|---|---|---|---|---|---|---|
| Publication Title: | Neuropsychologia | ||||||
| Creators: | O'Hare, L., Goodwin, P., Sharp, A., Contillo, A. and Pavan, A. | ||||||
| Publisher: | Elsevier | ||||||
| Date: | 15 October 2021 | ||||||
| Volume: | 161 | ||||||
| ISSN: | 0028-3932 | ||||||
| Identifiers: |
|
||||||
| Divisions: | Schools > School of Social Sciences | ||||||
| Record created by: | Laura Ward | ||||||
| Date Added: | 17 Aug 2021 13:27 | ||||||
| Last Modified: | 14 Aug 2022 03:00 | ||||||
| URI: | https://irep.ntu.ac.uk/id/eprint/44026 |
Actions (login required)
 |
Edit View |
Views
Views per month over past year
Downloads
Downloads per month over past year
