Testing of a dual-mode microwave care regimen for hydrogel lenses

Crabbe, A and Thompson, P, 2004. Testing of a dual-mode microwave care regimen for hydrogel lenses. Optometry and Vision Science, 81 (6), pp. 471-477. ISSN 1040-5488

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Abstract

Purpose. To test the design of a patient care regimen for soft lenses that aims to provide the highest standards of disinfecting through use of domestic microwave cookers, while also providing storage equipment and solution that enable patients to follow a conventional cold disinfecting regimen when traveling. The cleaning efficacy of surfactant agents during microwave treatment was also considered. Methods. The microbiologic performance of the regimen and its disinfecting apparatus was tested according to the Food and Drug Administration (FDA) protocols for contact lens heat disinfectors. Subsequently, a prospective pilot clinical trial of the regimen involving 15 subjects was carried out to the protocols of the FDA and International Standards Organization 11,980:1997. Results. Lenses inoculated with 107 colony-forming units (cfu) of Enterococcus faecalis were disinfected to 0 cfu by a 12-s irradiation of a compact disinfecting case that held the lenses suspended in 12 ml saline. A proof of operation indicator performed correctly for all 10 cases tested. No adverse reactions were found in the pilot patient trial, using Renu multipurpose (Bausch & Lomb, Rochester, NY) as the test solution, and no statistically significant difference was found between test and control groups in respect of any sign. However, the greater incidence of edema, palpebral hyperemia, and lens front-surface deposition in the microwave test group may be clinically significant.

Item Type:	Journal article
Publication Title:	Optometry and Vision Science
Creators:	Crabbe, A. and Thompson, P.
Publisher:	Lippincott Williams & Wilkins
Place of Publication:	Philadelphia, PA
Date:	2004
Volume:	81
Number:	6
ISSN:	1040-5488
Identifiers:	Number Type 1040-5488/04/8106-0471/0 Other
Divisions:	Schools > School of Art and Design
Record created by:	EPrints Services
Date Added:	09 Oct 2015 10:46
Last Modified:	23 Aug 2016 09:12
URI:	https://irep.ntu.ac.uk/id/eprint/17992

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