Genomic characterization of Campylobacter jejuni strain M1

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Friis, C., Wassenaar, T.M., Javed, M.A., Snipen, L., Lagesen, K., Hallin, P.F., Newell, D.G., Toszeghy, M., Ridley, A., Manning, G. and Ussery, D.W., 2010. Genomic characterization of Campylobacter jejuni strain M1. Plos One, 5 (8). ISSN 1932-6203

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Abstract

Campylobacter jejuni strain M1 (laboratory designation 99/308) is a rarely documented case of direct transmission of C. jejuni from chicken to a person, resulting in enteritis. We have sequenced the genome of C. jejuni strain M1, and compared this to 12 other C. jejuni sequenced genomes currently publicly available. Compared to these, M1 is closest to strain 81116. Based on the 13 genome sequences, we have identified the C. jejuni pan-genome, as well as the core genome, the auxiliary genes, and genes unique between strains M1 and 81116. The pan-genome contains 2,427 gene families, whilst the core genome comprised 1,295 gene families, or about two-thirds of the gene content of the average of the sequenced C. jejuni genomes. Various comparison and visualization tools were applied to the 13 C. jejuni genome sequences, including a species pan and core genome plot, a BLAST Matrix and a BLAST Atlas. Trees based on 16S rRNA sequences and on the total gene families in each genome are presented. The findings are discussed in the background of the proven virulence potential of M1.

Item Type:	Journal article
Publication Title:	Plos One
Creators:	Friis, C., Wassenaar, T.M., Javed, M.A., Snipen, L., Lagesen, K., Hallin, P.F., Newell, D.G., Toszeghy, M., Ridley, A., Manning, G. and Ussery, D.W.
Publisher:	Public Library of Science
Date:	2010
Volume:	5
Number:	8
ISSN:	1932-6203
Rights:	Creative Commons Attribution License (CCAL)
Divisions:	Schools > School of Science and Technology
Record created by:	EPrints Services
Date Added:	09 Oct 2015 11:05
Last Modified:	19 Oct 2015 14:41
URI:	https://irep.ntu.ac.uk/id/eprint/22701