Winter, JA ORCID: https://orcid.org/0000-0003-3582-7596 and Bunting, KA, 2012. Rings in the Extreme: PCNA Interactions and Adaptations in the Archaea. Archaea, 2012, pp. 1-8. ISSN 1472-3646
Preview |
Text
PubSub3638_Winter.pdf - Published version Download (3MB) | Preview |
Abstract
Biochemical and structural analysis of archaeal proteins has enabled us to gain great insight into many eukaryotic processes, simultaneously offering fascinating glimpses into the adaptation and evolution of proteins at the extremes of life. The archaeal PCNAs, central to DNA replication and repair, are no exception. Characterisation of the proteins alone, and in complex with both peptides and protein binding partners, has demonstrated the diversity and subtlety in the regulatory role of these sliding clamps. Equally, studies have provided valuable detailed insight into the adaptation of protein interactions and mechanisms that are necessary for life in extreme environments.
Item Type: | Journal article |
---|---|
Publication Title: | Archaea |
Creators: | Winter, J.A. and Bunting, K.A. |
Publisher: | Hindawi Publishing Corporation |
Date: | 2012 |
Volume: | 2012 |
ISSN: | 1472-3646 |
Identifiers: | Number Type 10.1155/2012/951010 DOI |
Divisions: | Schools > School of Science and Technology |
Record created by: | Linda Sullivan |
Date Added: | 10 Nov 2015 09:40 |
Last Modified: | 09 Jun 2017 13:56 |
URI: | https://irep.ntu.ac.uk/id/eprint/26209 |
Actions (login required)
Edit View |
Statistics
Views
Views per month over past year
Downloads
Downloads per month over past year