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Wang, K 
ORCID: https://orcid.org/0000-0001-5485-7091, Venetsanos, DT, Wang, J and Pierscionek, BK ORCID: https://orcid.org/0000-0002-8661-6353,
2018.
Combined use of parallel-plate compression and finite element modeling to analyze the mechanical properties of intact porcine lens.
Journal of Mechanics in Medicine and Biology, 18 (7): 1840013.
ISSN 0219-5194
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Abstract
The objective of this study is to explore the feasibility of a compression test for measuring mechanical properties of intact eye lenses using novel parallel plate compression equipment to compare the accuracy of implementing a classical Hertzian model and a newly proposed adjusted Hertzian model to calculate Young’s modulus from compression test results using finite element (FE) analysis. Parallel-plate compression tests were performed on porcine lenses. An axisymmetric FE model was developed to simulate the experimental process to evaluate the accuracy of using the classical Hertzian theory of contact mechanics as well as a newly proposed adjusted Hertzian theory model for calculating the equivalent Young’s modulus. By fitting the force-displacement relation obtained from FE simulations to both the classical and adjusted Hertzian theory model and comparing the calculated modulus to the input modulus of the FE model, the results demonstrated that the classical Hertzian theory model overestimated the Young’s modulus with a proportional error of over 10%. The adjusted Hertzian theory model produced results that are closer to original input values with error ratios all lower than 1.29%. Measurements of three porcine lenses from the parallel plate compression experiments were analyzed with resulting values of Young’s modulus of between 3.2kPa and 4.3kPa calculated. This study demonstrates that the adjusted Hertzian theory of contact mechanics can be applied in conjunction with the parallel-plate compression system to investigate the overall mechanical behavior of intact lenses.
| Item Type: | Journal article |
|---|---|
| Publication Title: | Journal of Mechanics in Medicine and Biology |
| Creators: | Wang, K., Venetsanos, D.T., Wang, J. and Pierscionek, B.K. |
| Publisher: | World Scientific Publishing |
| Date: | November 2018 |
| Volume: | 18 |
| Number: | 7 |
| ISSN: | 0219-5194 |
| Identifiers: | Number Type 10.1142/s0219519418400134 DOI |
| Divisions: | Schools > School of Science and Technology |
| Record created by: | Jonathan Gallacher |
| Date Added: | 27 Nov 2018 16:44 |
| Last Modified: | 01 Nov 2019 03:00 |
| URI: | https://irep.ntu.ac.uk/id/eprint/35148 |
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