Contributions of shape and stiffness to accommodative loss in the ageing human lens: a finite element model assessment

Wang, K ORCID: https://orcid.org/0000-0001-5485-7091, Hoshino, M, Uesugi, K, Yagi, N and Pierscionek, BK ORCID: https://orcid.org/0000-0002-8661-6353, 2019. Contributions of shape and stiffness to accommodative loss in the ageing human lens: a finite element model assessment. Journal of the Optical Society of America A, 36 (4), B116-B122. ISSN 1084-7529

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Abstract

Ageing changes to the various components of the accommodative system of the eye lens contribute to the loss of focusing power. The relative contributions of each ageing component, however, are not well defined. This study investigates the contribution of geometric parameters and material properties on accommodation, simulated using models based on human lenses aged 16, 35, and 48 years. Each model was tested using two different sets of material properties and a range of zonular fiber angles and was compared to results from in vivo measurements. The geometries and material parameters of older and younger lens models were interchanged to investigate the role of shape and material on accommodative capacity. Results indicate that geometry has the greater role in accommodation.

Item Type:	Journal article
Publication Title:	Journal of the Optical Society of America A
Creators:	Wang, K., Hoshino, M., Uesugi, K., Yagi, N. and Pierscionek, B.K.
Date:	1 April 2019
Volume:	36
Number:	4
ISSN:	1084-7529
Identifiers:	Number Type 10.1364/josaa.36.00b116 DOI
Divisions:	Schools > School of Science and Technology
Record created by:	Jonathan Gallacher
Date Added:	29 Mar 2019 16:42
Last Modified:	29 Mar 2019 16:42
URI:	https://irep.ntu.ac.uk/id/eprint/36148

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