Hormonal factors in the control of the browning of white adipose tissue

Hu, J and Christian, M ORCID: https://orcid.org/0000-0002-1616-4179, 2017. Hormonal factors in the control of the browning of white adipose tissue. Hormone Molecular Biology and Clinical Investigation, 31 (1): 20170017. ISSN 1868-1883

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Abstract

Adipose tissue has been historically classified into anabolic white adipose tissue (WAT) and catabolic brown adipose tissue (BAT). Recent studies have revealed the plasticity of WAT, where white adipocytes can be induced into ‘brown-like’ heat-producing adipocytes (BRITE or beige adipocytes). Recruiting and activating BRITE adipocytes in WAT (so-called ‘browning’) is believed to provide new avenues for the treatment of obesity-related diseases. A number of hormonal factors have been found to regulate BRITE adipose development and activity through autocrine, paracrine and systemic mechanisms. In this mini-review we will discuss the impact of these factors on the browning process, especially those hormonal factors identified with direct effects on white adipocytes.

Item Type:	Journal article
Publication Title:	Hormone Molecular Biology and Clinical Investigation
Creators:	Hu, J. and Christian, M.
Publisher:	Walter de Gruyter
Date:	2017
Volume:	31
Number:	1
ISSN:	1868-1883
Identifiers:	Number Type 10.1515/hmbci-2017-0017 DOI
Divisions:	Schools > School of Science and Technology
Record created by:	Jonathan Gallacher
Date Added:	12 Aug 2019 08:30
Last Modified:	12 Aug 2019 08:30
URI:	https://irep.ntu.ac.uk/id/eprint/37218

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