Mitochondrial D-loop sequence variation and maternal lineage in the endangered Cleveland Bay horse

Dell, AC, Curry, MC, Yarnell, KM ORCID: https://orcid.org/0000-0001-7464-8764, Starbuck, GR ORCID: https://orcid.org/0000-0002-6281-9885 and Wilson, PB ORCID: https://orcid.org/0000-0003-0207-2246, 2020. Mitochondrial D-loop sequence variation and maternal lineage in the endangered Cleveland Bay horse. PLoS ONE, 15 (12): e0243247.

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Abstract

Genetic diversity and maternal ancestry line relationships amongst a sample of 96 Cleveland Bay horses were investigated using a 479bp length of mitochondrial D-loop sequence. The analysis yielded at total of 11 haplotypes with 27 variable positions, all of which have been described in previous equine mitochondrial DNA d-loop studies. Four main haplotype clusters were present in the Cleveland Bay breed describing 89% of the total sample. This suggests that only four principal maternal ancestry lines exist in the present-day global Cleveland Bay population. Comparison of these sequences with other domestic horse haplotypes (Fig 2) shows a close association of the Cleveland Bay horse with Northern European (Clade C), Iberian (Clade A) and North African (Clade B) horse breeds. This indicates that the Cleveland Bay horse may not have evolved exclusively from the now extinct Chapman horse, as previous work as suggested. The Cleveland Bay horse remains one of only five domestic horse breeds classified as Critical on the Rare Breeds Survival Trust (UK) Watchlist and our results provide important information on the origins of this breed and represent a valuable tool for conservation purposes.

Item Type:	Journal article
Publication Title:	PLoS ONE
Creators:	Dell, A.C., Curry, M.C., Yarnell, K.M., Starbuck, G.R. and Wilson, P.B.
Publisher:	Public Library of Science (PLoS)
Date:	3 December 2020
Volume:	15
Number:	12
Identifiers:	Number Type 10.1371/journal.pone.0243247 DOI 1394324 Other
Rights:	Copyright: © 2020 Dell et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Divisions:	Schools > School of Animal, Rural and Environmental Sciences
Record created by:	Linda Sullivan
Date Added:	14 Dec 2020 14:44
Last Modified:	31 May 2021 15:07
URI:	https://irep.ntu.ac.uk/id/eprint/41853

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