Italian version of the short 10/66 dementia diagnostic schedule: a validation study

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Ibnidris, A, Piumatti, G, Carlevaro, F, Fadda, M, Magno, F, Magistro, D ORCID: https://orcid.org/0000-0002-2554-3701 and Albanese, E, 2021. Italian version of the short 10/66 dementia diagnostic schedule: a validation study. BMJ Open, 11 (6): e045867. ISSN 2044-6055

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Official URL: https://doi.org/10.1136/bmjopen-2020-045867

Abstract

Objectives: To determine the criterion and concurrent validity of the Italian version of the short 10/66 Dementia Diagnostic Schedule and algorithm in a sample of Italian native speakers, older adults.

Design: A cross-sectional, validation study.

Setting: The study was conducted with older adults living in the community and in nursing homes in the Canton of Ticino, Switzerland, and the Piedmont region in Italy between March and August 2019.

Participants: A convenience sample of 229 participants (69% females) were recruited. The eligibility criteria were being ≥60 years old and having an informant. The final sample included 74 participants (32%) with a previous clinical diagnosis of dementia and 155 (68%) cognitively healthy older adults.

Primary and secondary outcome measures: The short version of 10/66 Dementia Diagnostic Schedule consists of the Community Screening Instrument for Dementia, the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) 10-word list learning task with delayed recall and the depression scale, Euro-Depression (EURO-D) scale. Disability was measured using the WHO Disability Assessment Schedule (WHO-DAS II).

Results: The Italian version of the short 10/66 Dementia Diagnostic Schedule showed fair sensitivity (87%), specificity (61%) and agreement with the clinical diagnosis of dementia (kappa=0.40, area under the receiver operating characteristics curve=0.74). Older adults with dementia living in nursing homes had higher disability scores (WHO-DAS II mean=23.14, SE=1.29) than those living in the community (WHO-DAS II mean=7.08, SE=0.66). WHO-DAS II was positively correlated with the short version of the 10/66 dementia diagnosis (β=5.23, 95% CI 2.05 to 8.41).

Conclusions: In settings where lengthy diagnostic procedures are not feasible, the short 10/66 is a practical tool to identify dementia in older adults. Our findings extend evidence on the validity of the 10/66 dementia diagnostic algorithm to high-income countries, where epidemiological evidence on dementia and its impact is outdated.

Item Type:	Journal article
Publication Title:	BMJ Open
Creators:	Ibnidris, A., Piumatti, G., Carlevaro, F., Fadda, M., Magno, F., Magistro, D. and Albanese, E.
Publisher:	BMJ
Date:	30 June 2021
Volume:	11
Number:	6
ISSN:	2044-6055
Identifiers:	Number Type 10.1136/bmjopen-2020-045867 DOI 1449431 Other
Rights:	© Author(s) (or their employer(s)) 2021. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
Divisions:	Schools > School of Science and Technology
Record created by:	Laura Ward
Date Added:	05 Jul 2021 10:46
Last Modified:	05 Jul 2021 10:46
URI:	https://irep.ntu.ac.uk/id/eprint/43309