Cellulose-deconstruction potential of nano-biocatalytic systems: A strategic drive from designing to sustainable applications of immobilized cellulases

Qamar, SA, Qamar, M, Bilal, M, Bharagava, RN, Ferreira, LFR, Sher, F ORCID: https://orcid.org/0000-0003-2890-5912 and Iqbal, HMN, 2021. Cellulose-deconstruction potential of nano-biocatalytic systems: A strategic drive from designing to sustainable applications of immobilized cellulases. International Journal of Biological Macromolecules, 185, pp. 1-19. ISSN 0141-8130

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Abstract

Nanostructured materials along with an added value of polymers-based support carriers have gained high interest and considered ideal for enzyme immobilization. The recently emerged nanoscience interface in the form of nanostructured materials combined with immobilized-enzyme-based bio-catalysis has now become research and development frontiers in advance and applied bio-catalysis engineering. With the involvement of nanoscience, various polymers have been thoroughly developed and exploited to nanostructured engineer constructs as ideal support carriers/matrices. Such nanotechnologically engineered support carriers/matrix possesses unique structural, physicochemical, and functional attributes which equilibrate principal factors and strengthen the biocatalysts efficacy for multipurpose applications. In addition, nano-supported catalysts are potential alternatives that can outstrip several limitations of conventional biocatalysts, such as reduced catalytic efficacy and turnover, low mass transfer efficiency, instability during the reaction, and most importantly, partial, or complete inhibition/deactivation. In this context, engineering robust and highly efficient biocatalysts is an industrially relevant prerequisite. This review comprehensively covered various biopolymers and nanostructured materials, including silica, hybrid nanoflower, nanotubes or nanofibers, nanomembranes, graphene oxide nanoparticles, metal-oxide frameworks, and magnetic nanoparticles as robust matrices for cellulase immobilization. The work is further enriched by spotlighting applied and industrially relevant considerations of nano-immobilized cellulases. For instance, owing to the cellulose-deconstruction features of nano-immobilized cellulases, the applications like lignocellulosic biomass conversion into industrially useful products or biofuels, improved paper sheet density and pulp beat in paper and pulp industry, fruit juice clarification in food industry are evident examples of cellulases, thereof are discussed in this work.

Item Type:	Journal article
Publication Title:	International Journal of Biological Macromolecules
Creators:	Qamar, S.A., Qamar, M., Bilal, M., Bharagava, R.N., Ferreira, L.F.R., Sher, F. and Iqbal, H.M.N.
Publisher:	Elsevier B.V.
Date:	31 August 2021
Volume:	185
ISSN:	0141-8130
Identifiers:	Number Type 10.1016/j.ijbiomac.2021.06.079 DOI 1489698 Other
Divisions:	Schools > School of Science and Technology
Record created by:	Laura Ward
Date Added:	08 Mar 2022 12:20
Last Modified:	17 Jun 2022 03:00
URI:	https://irep.ntu.ac.uk/id/eprint/45817

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