Adverse drug reaction monitoring and reporting among physicians and pharmacists in Pakistan: a cross-sectional study

Nisa, ZU, Zafar, A, Zafar, F, Pezaro, S and Sher, F ORCID: https://orcid.org/0000-0003-2890-5912, 2020. Adverse drug reaction monitoring and reporting among physicians and pharmacists in Pakistan: a cross-sectional study. Current Drug Safety, 15 (2), pp. 137-146. ISSN 1574-8863

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Abstract

Background: The success of a reporting system of adverse drug reaction (ADR) depends on the knowledge, attitudes, and practices of the health care professionals. However, due to a lack of knowledge and poor contribution by healthcare workers, ADR remains underreported. To improve safety, proper identification and ADR reporting is necessary.

Objective: This study was carried out to determine knowledge, attitude, and practices of ADR among physicians and pharmacists working in Pakistan and the factors which encourage and discourage effective reporting.

Methods: A cross-sectional study was conducted using a pretested questionnaire. Questionnaires were distributed among 333 physicians and 34 pharmacists with a 95.5% response rate. The Statistical Package for Social Science (SPSS) was used for data analysis.

Results: Pharmacists have more knowledge regarding ADR compared to physicians (47.1% vs. 13.8%, p < 0.001). Pharmacists also have a positive attitude compared to physicians (97.1% vs. 76.3%, p < 0.001). No significant difference was noticed in ADR practice by physicians and pharmacists (12.3% vs. 11.8, p = 0.92). The seriousness of ADR was the main factor that encouraged nearly all pharmacists to report, whereas among physician’s, seriousness and the unusualness of reaction, the new drug involvement, and confidence in diagnosis were the factors which encouraged them to report ADR.

Conclusion: Overall, pharmacists had more knowledge and a positive attitude regarding ADR reporting compared to physicians, but practices of ADR reporting remained the same among both. Therefore, it is suggested that educational interventions, along with training programs, should be developed.

Item Type:	Journal article
Publication Title:	Current Drug Safety
Creators:	Nisa, Z.U., Zafar, A., Zafar, F., Pezaro, S. and Sher, F.
Publisher:	Bentham Science Publishers Ltd.
Date:	19 June 2020
Volume:	15
Number:	2
ISSN:	1574-8863
Identifiers:	Number Type 10.2174/1574886315666200427120322 DOI 1568092 Other
Rights:	The published manuscript is available at EurekaSelect via http://www.eurekaselect.com/10.2174/1574886315666200427120322
Divisions:	Schools > School of Science and Technology
Record created by:	Laura Ward
Date Added:	26 Jul 2022 15:13
Last Modified:	26 Jul 2022 15:13
URI:	https://irep.ntu.ac.uk/id/eprint/46733

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