What do we know about non-epileptic seizures in adults with intellectual disability: a narrative review

Rawlings, GH ORCID: https://orcid.org/0000-0003-4962-3551, Novakova, B, Beail, N and Reuber, M, 2021. What do we know about non-epileptic seizures in adults with intellectual disability: a narrative review. Seizure - European Journal of Epilepsy, 91, pp. 437-446. ISSN 1059-1311

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Abstract

Psychogenic non-epileptic seizures (PNES) superficially resemble epileptic seizures, but are not associated with abnormal electrical activity in the brain. PNES are a heterogeneous entity and while there is increasing interest in the characterisation of PNES sub-groups, little is known about individuals with PNES who have an intellectual disability (ID). ID is a lifelong condition characterised by significant limitations in cognitive, social and practical skills. ID (commonly with comorbid epilepsy) has been identified as a risk factor for developing PNES. However, people with ID are often excluded from research in PNES. This has unfortunately resulted in a lack of evidence to help inform practice and policy for this population. This narrative review synthesises the currently available evidence in terms of the epidemiology, demographic and clinical profile of adults with PNES and ID. There is a particular focus on demographics, aetiological factors, PNES characteristics, diagnosis and treatment of the condition in this population. Throughout this article, we critique the existing evidence, discuss implications for clinical practice and highlight the need for further research and enquiry. What emerges from the evidence is that, even within the sub-group of those with ID, PNES are a heterogeneous condition. Individuals with ID and PNES are likely to present with diverse and complex needs requiring multidisciplinary care. This review is aimed at the broad range of healthcare professionals who may encounter this group. We hope that it will stimulate further discussion and research initiatives.

Item Type:	Journal article
Publication Title:	Seizure - European Journal of Epilepsy
Creators:	Rawlings, G.H., Novakova, B., Beail, N. and Reuber, M.
Publisher:	Elsevier
Date:	1 October 2021
Volume:	91
ISSN:	1059-1311
Identifiers:	Number Type 10.1016/j.seizure.2021.07.021 DOI 1542061 Other
Divisions:	Schools > School of Social Sciences
Record created by:	Laura Ward
Date Added:	12 Dec 2022 12:23
Last Modified:	23 Jan 2023 12:23
URI:	https://irep.ntu.ac.uk/id/eprint/47627

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