Embracing uncertainty flexibility: harnessing a supervised tree kernel to empower ensemble modelling for 2D echocardiography-based prediction of right ventricular volume

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Bohoran, TA ORCID: https://orcid.org/0000-0001-8510-579X, Kampaktsis, PN, McLaughlin, L, Leb, J, Moustakidis, S, McCann, GP and Giannakidis, A ORCID: https://orcid.org/0000-0001-7403-923X, 2024. Embracing uncertainty flexibility: harnessing a supervised tree kernel to empower ensemble modelling for 2D echocardiography-based prediction of right ventricular volume. In: Osten, W, ed., Proceedings of SPIE: Sixteenth International Conference on Machine Vision (ICMV 2023). Bellingham, Washington: SPIE. ISBN 9781510674622

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Official URL: https://doi.org/10.1117/12.3023433

Abstract

The right ventricular (RV) function deterioration strongly predicts clinical outcomes in numerous circumstances. To boost the clinical deployment of ensemble regression methods that quantify RV volumes using tabular data from the widely available two-dimensional echocardiography (2DE), we propose to complement the volume predictions with uncertainty scores. To this end, we employ an instance-based method which uses the learned tree structure to identify the nearest training samples to a target instance and then uses a number of distribution types to more flexibly model the output. The probabilistic and point-prediction performances of the proposed framework are evaluated on a relatively small-scale dataset, comprising 100 end-diastolic and end-systolic RV volumes. The reference values for point performance were obtained from MRI. The results demonstrate that our flexible approach yields improved probabilistic and point performances over other state-of-the art methods. The appropriateness of the proposed framework is showcased by providing exemplar cases. The estimated uncertainty embodies both aleatoric and epistemic types. This work aligns with trustworthy artificial intelligence since it can be used to enhance the decision-making process and reduce risks. The feature importance scores of our framework can be exploited to reduce the number of required 2DE views which could enhance the proposed pipeline’s clinical application.

Item Type:	Chapter in book
Creators:	Bohoran, T.A., Kampaktsis, P.N., McLaughlin, L., Leb, J., Moustakidis, S., McCann, G.P. and Giannakidis, A.
Publisher:	SPIE
Place of Publication:	Bellingham, Washington
Date:	3 April 2024
Volume:	13072
ISBN:	9781510674622
Identifiers:	Number Type 10.1117/12.3023433 DOI 1883580 Other
Divisions:	Schools > School of Science and Technology
Record created by:	Jonathan Gallacher
Date Added:	10 Apr 2024 09:16
Last Modified:	10 Apr 2024 09:16
URI:	https://irep.ntu.ac.uk/id/eprint/51225