Ceramic conversion treated titanium implant abutments with gold for enhanced antimicrobial activity

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Aly, YM, Zhang, Z, Ali, N, Milward, MR, Poologasundarampillai, G, Dong, H, Kuehne, SA ORCID: https://orcid.org/0000-0001-6790-8433 and Camilleri, J, 2024. Ceramic conversion treated titanium implant abutments with gold for enhanced antimicrobial activity. Dental Materials, 40 (8), pp. 1199-1207. ISSN 0109-5641

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Official URL: https://doi.org/10.1016/j.dental.2024.05.029

Abstract

Introduction: Peri-implantitis is an inflammatory process around dental implants that is characterised by bone loss that may jeopardize the long-term survival of osseo integrated dental implants. The aim of this study was to create a surface coating on titanium abutments that possesses cellular adhesion and anti-microbial properties as a post-implant placement strategy for patients at risk of peri-implantitis.

Materials and Methods: Titanium alloy Grade V stubs were coated with gold particles and then subjected to ceramic conversion treatment (CCT) at 620 °C for 3, 8 and 80 h. The surface characteristics and chemistry were assessed using scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analysis. The leaching profile was investigated by inductively coupled plasma mass spectroscopy (ICP-MS) for all groups after 7, 14 and 28 days in contact with distilled water. A scratch test was conducted to assess the adhesion of the gold coating to the underlying titanium discs. Two bacterial species (Staphylococcus aureus (SA) & Fusobacterium nucleatum (FN)) were used to assess the antibacterial behaviour of the coated discs using a direct attachment assay test. The potential changes in surface chemistry by the bacterial species were investigated by grazing angle XRD.

Results: The gold pre-coated titanium discs exhibited good stability of the coating especially after immersion in distilled water and after bacterial colonisation as evident by XRD analysis. Good surface adhesion of the coating was demonstrated for gold treated discs after scratch test analysis, especially titanium, following a 3-hour (3 H) ceramic conversion treatment. All coated discs exhibited significantly improved antimicrobial properties against both tested bacterial species compared to untreated titanium discs.

Conclusions: Ceramic conversion treated titanium with a pre-deposited gold layer showed improved antimicrobial properties against both SA and FN species than untreated Ti-C discs. Scratch test analysis showed good adherence properties of the coated discs the oxide layer formed is firmly adherent to the underlying titanium substrate, suggesting that this approach may have clinical efficacy for coating implant abutments.

Item Type:	Journal article
Publication Title:	Dental Materials
Creators:	Aly, Y.M., Zhang, Z., Ali, N., Milward, M.R., Poologasundarampillai, G., Dong, H., Kuehne, S.A. and Camilleri, J.
Publisher:	Elsevier
Date:	August 2024
Volume:	40
Number:	8
ISSN:	0109-5641
Identifiers:	Number Type 10.1016/j.dental.2024.05.029 DOI 2189344 Other
Rights:	© 2024 the author(s). Published by Elsevier Inc. on behalf of The Academy of Dental Materials. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Divisions:	Schools > School of Science and Technology
Record created by:	Jonathan Gallacher
Date Added:	07 Aug 2024 10:58
Last Modified:	07 Aug 2024 10:58
URI:	https://irep.ntu.ac.uk/id/eprint/51936