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Hall, J 
ORCID: https://orcid.org/0009-0004-8314-5228, Mekapothula, S ORCID: https://orcid.org/0000-0002-3906-842X, Coxhill, R, Craske, D ORCID: https://orcid.org/0000-0003-3564-4108, Varney, AM ORCID: https://orcid.org/0000-0002-5943-161X, Cave, GWV ORCID: https://orcid.org/0000-0002-4167-1332 and McLean, S ORCID: https://orcid.org/0000-0001-8551-4307,
2024.
Surface-functionalised copper oxide nanoparticles: a pathway to multidrug-resistant pathogen control in medical devices.
Nanomaterials, 14 (23): 1899.
ISSN 2079-4991
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Abstract
Copper oxide nanoparticles (CuONPs) offer promising antimicrobial properties against a range of pathogens, addressing the urgent issue of antibiotic resistance. This study details the synthesis of glutamic acid-coated CuONPs (GA-CuONPs) and their functionalisation on medical-grade silicone tubing, using an oxysilane bonding agent. The resulting coating shows significant antimicrobial activity against both Gram-positive and Gram-negative bacteria, including multidrug-resistant strains, while remaining non-toxic to human cells and exhibiting stable adherence, without leaching. This versatile coating method can be applied during manufacturing, or for ad hoc modifications, enhancing the antimicrobial properties of medical devices.
| Item Type: | Journal article |
|---|---|
| Publication Title: | Nanomaterials |
| Creators: | Hall, J., Mekapothula, S., Coxhill, R., Craske, D., Varney, A.M., Cave, G.W.V. and McLean, S. |
| Publisher: | MDPI |
| Date: | 1 December 2024 |
| Volume: | 14 |
| Number: | 23 |
| ISSN: | 2079-4991 |
| Identifiers: | Number Type 10.3390/nano14231899 DOI 2300818 Other |
| Rights: | © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| Divisions: | Schools > School of Science and Technology |
| Record created by: | Melissa Cornwell |
| Date Added: | 12 Dec 2024 09:40 |
| Last Modified: | 12 Dec 2024 09:40 |
| URI: | https://irep.ntu.ac.uk/id/eprint/52713 |
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