Dai, X ORCID: https://orcid.org/0009-0008-8757-6470, Ren, T, Williams, G
ORCID: https://orcid.org/0000-0001-7689-1231, Jones, G
ORCID: https://orcid.org/0000-0003-3867-9947, Li, F, Du, W
ORCID: https://orcid.org/0000-0002-5115-7214 and Hua, J,
2025.
A bio‐ecological model for early screening of developmental coordination disorder.
Developmental Medicine and Child Neurology.
ISSN 0012-1622
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Abstract
Aim: To develop and externally validate a bio-ecological model for early screening of developmental coordination disorder (DCD) using maternal and environmental risk factors from electronic health records, aimed at improving early detection in children under 5 years.
Method: This was a prospective study that examined data from 150 948 preschool children in China. Perinatal and sociodemographic predictors were integrated using logistic regression and random forest algorithms. The model was internally validated on split training and testing subsets and externally validated on an independent clinical sample of 1359 children aged 3 to 10 years, including confirmed diagnoses of DCD. Model performance was evaluated using the area under the curve (AUC), sensitivity, specificity, and accuracy.
Results: In the group aged 3 to 5 years, the model achieved an AUC of 0.70, sensitivity of 71.43%, accuracy of 77.61%, and specificity of 78.00%. In the group aged 6 to 10 years, performance was moderate (AUC = 0.58; sensitivity = 54.88%; accuracy = 61.50%; specificity = 62.28%).
Interpretation: This bio-ecological model offers a scalable, cost-effective tool to support the early identification of DCD using electronic health record data. It performs well in early childhood and maintains moderate accuracy in older children, supporting its utility for longer-term risk prediction. The model could enhance existing screening systems by enabling earlier triage and intervention. Further validation across diverse health care settings is warranted.
Item Type: | Journal article |
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Publication Title: | Developmental Medicine and Child Neurology |
Creators: | Dai, X., Ren, T., Williams, G., Jones, G., Li, F., Du, W. and Hua, J. |
Publisher: | Wiley |
Date: | 3 October 2025 |
ISSN: | 0012-1622 |
Identifiers: | Number Type 10.1111/dmcn.70000 DOI 2509118 Other |
Rights: | © 2025 The Author(s). Developmental Medicine & Child Neurology published by John Wiley & Sons Ltd on behalf of Mac Keith Press. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
Divisions: | Schools > School of Social Sciences |
Record created by: | Laura Borcherds |
Date Added: | 07 Oct 2025 15:02 |
Last Modified: | 07 Oct 2025 15:02 |
URI: | https://irep.ntu.ac.uk/id/eprint/54517 |
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