Items where Author is "Turner, MD"

HABRA, K., PEARSON, J.R.D., LE VU, P., PUIG‐SAENZ, C., CRIPPS, M.J., KHAN, M.A., TURNER, M.D., SALE, C. and MCARDLE, S.E.B., 2023. Anticancer actions of carnosine in cellular models of prostate cancer. Journal of Cellular and Molecular Medicine. ISSN 1582-1838

TARUM, J., DEGENS, H., TURNER, M.D., STEWART, C., SALE, C. and SANTOS, L., 2023. Modelling skeletal muscle ageing and repair in vitro. Journal of Tissue Engineering and Regenerative Medicine, 2023: 9802235. ISSN 1932-6254

TORABI, F., VADAKEKOLATHU, J., WYATT, R., LEETE, P., TOMBS, M.A., RICHARDSON, C.C., BOOCOCK, D.J., TURNER, M.D., MORGAN, N.G., RICHARDSON, S.J. and CHRISTIE, M.R., 2023. Differential expression of genes controlling lymphocyte differentiation and migration in two distinct endotypes of type 1 diabetes. Diabetic Medicine. ISSN 0742-3071

MATTHEWS, J.J., TURNER, M.D., SANTOS, L., ELLIOTT-SALE, K.J. and SALE, C., 2023. Carnosine increases insulin-stimulated glucose uptake and reduces methylglyoxal-modified proteins in type-2 diabetic human skeletal muscle cells. Amino Acids. ISSN 0939-4451

AL SHUHOUMI, M.A., AL WAILI, A. and TURNER, M.D., 2023. Life and maladies in the grey area between the up & down regulation of GATA6: uncharted spots of beta-pancreatic islet cells. International Journal of Clinical Biochemistry and Research, 10 (4), pp. 302-313. ISSN 2394-6369

BILLACURA, M.P., JR LAVILLA, C., CRIPPS, M.J., HANNA, K., SALE, C. and TURNER, M.D., 2022. β-alanine scavenging of free radicals protects mitochondrial function and enhances both insulin secretion and glucose uptake in cells under metabolic stress. Advances in Redox Research, 6: 100050.

TARUM, J., TURNER, M.D., SALE, C., STEWART, C.E., DEGENS, H. and SANTOS, L., 2022. In vitro regeneration capacity in response to chemical injury is compromised in aged vs young muscle cells: 2099. Medicine and Science in Sports and Exercise, 54 (9S), p. 614. ISSN 1530-0315

CREIGHTON, J.V., DE SOUZA GONÇALVES, L., ARTIOLI, G.G., TAN, D., ELLIOTT-SALE, K.J., TURNER, M.D., DOIG, C.L. and SALE, C., 2022. Physiological roles of carnosine in myocardial function and health. Advances in Nutrition. ISSN 2156-5376

TURNER, M.D., SALE, C., GARNER, A.C. and HIPKISS, A.R., 2021. Anti-cancer actions of carnosine and the restoration of normal cellular homeostasis. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1868 (11): 119117. ISSN 0167-4889

LAVILLA, C.J., BILLACURA, M.P., HANNA, K., BOOCOCK, D.J., COVENEY, C., MILES, A.K., FOULDS, G.A., MURPHY, A., TAN, A., JACKISCH, L., SAYERS, S.R., CATON, P.W., DOIG, C.L., MCTERNAN, P.G., COLOMBO, S.L., SALE, C. and TURNER, M.D., 2021. Carnosine protects stimulus-secretion coupling through prevention of protein carbonyl adduction events in cells under metabolic stress. Free Radical Biology and Medicine. ISSN 0891-5849

MATTHEWS, J.J., DOLAN, E., SWINTON, P.A., SANTOS, L., ARTIOLI, G.G., TURNER, M.D., ELLIOTT-SALE, K.J. and SALE, C., 2021. Effect of carnosine or β-alanine supplementation on markers of glycemic control and insulin resistance in humans and animals: a systematic review and meta-analysis. Advances in Nutrition. ISSN 2156-5376

HEWAWASAM, N.V., LHAF, F., TAYLOR, H.A., VILORIA, K., AUSTIN, A., KING, A., JONES, P., JONES, L., TURNER, M.D. and HILL, N.J., 2020. Modulation of Rab7a-mediated growth factor receptor trafficking inhibits islet beta cell apoptosis and autophagy under conditions of metabolic stress. Scientific Reports, 10 (1): 15741.

MATTHEWS, J.J., DOLAN, E., SWINTON, P.A., SANTOS, L., ARTIOLI, G.G., TURNER, M.D., ELLIOTT-SALE, K.J. and SALE, C., 2020. The effect of carnosine or β-alanine supplementation on markers of glycaemic control and insulin resistance in human and animal studies: a protocol for a systematic review and meta-analysis. Systematic Reviews, 9 (1): 282.

TURNER, M.D., GONZALEZ, L.L. and GARRIE, K., 2020. Role of S100 proteins in health and disease. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research: 118677. ISSN 0167-4889

CRIPPS, M.J., BAGNATI, M., JONES, T.A., OGUNKOLADE, B.W., SAYERS, S.R., CATON, P.W., HANNA, K., BILLACURA, M., FAIR, K., NELSON, C.P., LOWE, R., HITMAN, G.A., BERRY, M.D. and TURNER, M.D., 2020. Identification of a subset of trace amine-associated receptors and ligands as potential modulators of insulin secretion. Biochemical Pharmacology, 171: 113685. ISSN 0006-2952

MATTHEWS, J.J., ARTIOLI, G.G., TURNER, M.D. and SALE, C., 2019. The physiological roles of carnosine and β-alanine in exercising human skeletal muscle. Medicine & Science in Sports & Exercise, 51 (10), pp. 2098-2108. ISSN 0195-9131

GONZALEZ, L.L., GARRIE, K. and TURNER, M.D., 2018. Type 2 diabetes – an autoinflammatory disease driven by metabolic stress. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1864 (11), pp. 3805-3823. ISSN 0925-4439

TURNER, M.D., 2017. The identification of TNFR5 as a therapeutic target in diabetes. Expert Opinion on Therapeutic Targets. ISSN 1472-8222

CRIPPS, M.J., HANNA, K., LAVILLA, C., SAYERS, S.R., CATON, P.W., SIMS, C., DE GIROLAMO, L., SALE, C. and TURNER, M.D., 2017. Carnosine scavenging of glucolipotoxic free radicals enhances insulin secretion and glucose uptake. Scientific Reports, 7 (1), p. 13313. ISSN 2045-2322

BAGNATI, M., OGUNKOLADE, B.W., MARSHALL, C., TUCCI, C., HANNA, K., JONES, T.A., BUGLIANI, M., NEDJAI, B., CATON, P.W., KIESWICH, J., YAQOOB, M.M., BALL, G.R., MARCHETTI, P., HITMAN, G.A. and TURNER, M.D., 2016. Glucolipotoxicity initiates pancreatic β-cell death through 1 tumour necrosis factor receptor 5 (TNFR5 / CD40) mediated 2 STAT1 and NF-κB activation. Cell Death and Disease, 7, e2329. ISSN 2041-4889

SOMANATH, S., PARTRIDGE, C.J., MARSHALL, C., ROWE, T. and TURNER, M.D., 2016. Snapin mediates insulin secretory granule docking, but not trans-SNARE complex formation. Biochemical and Biophysical Research Communications, 473 (2), pp. 403-407. ISSN 0006-291X

TURNER, M.D., NEDJAI, B., HURST, T. and PENNINGTON, D.J., 2014. Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1843 (11), pp. 2563-2582. ISSN 0167-4889

TURNER, M.D., 2012. [Invited speaker]. In: OMICS International Conference on “Clinical & Cellular Immunology”, Chicago, 2012, Chicago.

TURNER, M.D., 2012. [Keynote speaker]. In: OMICS International Conference on “Clinical & Cellular Immunology”, Chicago, 2012, Chicago.

TURNER, M.D., CHAUDHRY, A. and NEDJAI, B., 2012. TNFR1 trafficking dysfunction opens the TRAPS door to proinflammatory cytokine secretion. Bioscience Reports, 32, pp. 105-112.

DOMINGUEZ, V., RAIMONDI, C., SOMANATH, S., BUGLIANI, M., LODER, M.K., EDLING, C.E., DIVECHA, N., DA SILVA-XAVIER, G., MARSELLI, L., PERSAUD, S.J., TURNER, M.D., RUTTER, G.A., MARCHETTI, P., FALASCA, M. and MAFFUCCI, T., 2011. Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells. Journal of Biological Chemistry, 286, pp. 4216-4225.

TURNER, M.D. and CHERNAJOVSKY, Y., 2011. Comment on: Low TNF-induced NF-kappaB and p38 phosphorylation levels in leucocytes in tumour necrosis factor receptor-associated periodic syndrome. Rheumatology, pp. 1525-1526.

NEDJAI, B., HITMAN, G.A., CHURCH, L.D., MINDEN, K., WHITEFORD, M.L., MCKEE, S., STJERNBERG, S., PETTERSSON, T., RANKI, A., HAWKINS, P., ARKWRIGHT, P.D., MCDERMOTT, M.F. and TURNER, M.D., 2011. Differential cytokine secretion resulting from p65 and c-Rel NF-kappaB subunit signaling in peripheral blood mononuclear cells of TNFR-associated periodic fever syndrome patients. Cell Immunology, 268, pp. 55-59.

TURNER, M.D., 2011. [Invited speaker]. In: Advances in Inflammation and Translational Medicine, London, 2011, London.

NEDJAI, B., QUILLINAN, N., COUGHLAN, R.J., CHURCH, L., MCDERMOTT, M.F., HITMAN, G.A. and TURNER, M.D., 2011. Lessons from anti-TNF biologics: infliximab failure in a TRAPS family with the T50M mutation in TNFRSF1A. Advances in Experimental Medicine and Biology, 691, pp. 409-419.

TURNER, M.D., 2010. [Invited speaker]. In: FASEB Conference on “The Biology of Calpains in Health and Disease”, Scottsdale, USA, 2010, Scottsdale, USA.

TURNER, M.D., 2010. [Invited speaker]. In: UK Membrane Trafficking, London, 2010, London.

PERSAUD, S.J., ARDEN, C., BERGSTEN, P., BONE, A.J., BROWN, J., DUNMORE, S., HARRISON, M., HAUGE-EVANS, A., KELLY, C., KING, A., MAFFUCCI, T., MARRIOTT, C.E., MCCLENAGHAN, N., MORGAN, N.G., REERS, C., RUSSELL, M., TURNER, M.D., WILLOUGHBY, E., YOUNIS, M.Y.G., ZHI, Z. and JONES, P.M., 2010. Pseudoislets as primary islet replacements for research. Islets, 2, pp. 236-239.

SOMANATH, S., BARG, S., MARSHALL, C., SILWOOD, C.J. and TURNER, M.D., 2009. High extracellular glucose inhibits exocytosis by disruption of syntaxin 1A-containing lipid rafts. Biochemical and Biophysical Research Communications, 389, pp. 241-246.

TURNER, M.D., 2009. [Invited speaker]. In: 12th International TNF Conference, Madrid, 2009, Madrid.

NEDJAI, B., HITMAN, G.A., QUILLINAN, N., COUGHLAN, R.J., CHURCH, L.D., MCDERMOTT, M.F. and TURNER, M.D., 2009. Proinflammatory action of the antiinflammatory drug infliximab in TNF-receptor associated periodic syndrome. Arthritis & Rheumatism, 60, pp. 619-625.

NEJADI, B., HITMAN, G.A., YOUSAF, N., CHERNAJOVSKY, Y., STJERNBERG, S., PETTERSSON, T., RANKI, A., HAWKINS, P., ARKWRIGHT, P.D., MCDERMOTT, M.F. and TURNER, M.D., 2008. Abnormal tumor necrosis factor receptor I cell surface expression and NF-kappaB activation in tumor necrosis factor receptor-associated periodic syndrome. Arthritis & Rheumatism, 58, pp. 273-283.

TURNER, M.D., HITMAN, G.A., NEDJAI, B. and MCDERMOTT, M., 2008. Cell surface expression of TNFR1 in tumor necrosis factor receptor associated periodic syndrome: reply. Arthritis & Rheumatism, 58, pp. 2214-2215.

CHURCHMAN, S.M., CHURCH, L.D., SAVIC, S., COULTHARD, L.R., HAYWARD, B., NEDJAI, B., TURNER, M.D., MATHEWS, R.J., BAGULEY, E., HITMAN, G.A., GOOI, H.C., WOOD, P.M.D., EMERY, P. and MCDERMOTT, M.F., 2008. A novel TNFRSF1A splice mutation associated with increased NF-kappaB transcription factor activation in patients with TNF-receptor associated periodic syndrome (TRAPS). Annals of the Rheumatic Diseases, 67, pp. 1589-1595.

TURNER, M.D., FULCHER, F.K., SMITH, B.T., VELASQUEZ, C.R., AGANNA, E., PARTRIDGE, C.J., HITMAN, G.A., CLARK, A. and PATEL, Y.M., 2007. Calpain facilitates actin reorganization during glucose-stimulated insulin secretion. Biochemical and Biophysical Research Communications, 352, pp. 650-655.

TURNER, M.D., 2007. Coordinated control of both insulin secretion and insulin action through calpain-10 mediated regulation of exocytosis? Molecular Genetics and Metabolism, 91, pp. 305-307.

MARSHALL, C., HITMAN, G.A., CASSELL, P.G. and TURNER, M.D., 2007. Effect of glucolipotoxicity and rosiglitazone upon insulin secretion. Biochemical and Biophysical Research Communications, 356, pp. 756-762.

EVANS, J.S. and TURNER, M.D., 2007. Emerging functions of the calpain superfamily of cysteine proteases in neuroendocrine secretory pathways. Journal of Neurochemistry, 103, pp. 849-859.

AGANNA, E., BURRIN, J.M., HITMAN, G.A. and TURNER, M.D., 2006. Involvement of calpain and synaptotagmin Ca2+ sensors in hormone secretion from excitable endocrine cells. Journal of Endocrinology, 190 (3), R1-R7. ISSN 0022-0795

LARA-LEMUS, R., LIU, M., TURNER, M.D., SCHERER, P., STENBECK, G., IYENGAR, P. and ARVAN, P., 2006. Lumenal protein sorting to the constitutive secretory pathway of a regulated secretory cell. Journal of Cell Science, 119, pp. 1833-1842.

TURNER, M.D., CASSELL, P.G. and HITMAN, G.A., 2005. Calpain-10: from genome search to function. Diabetes/Metabolism Research and Reviews, 21, pp. 505-514.

MARSHALL, C., HITMAN, G.A., PARTRIDGE, C.J., CLARK, A., MA, H., SHEARER, T.R. and TURNER, M.D., 2005. Evidence that an isoform of calpain-10 is a regulator of exocytosis in pancreatic beta-cells. Molecular Endocrinology, 19, pp. 213-224.

TURNER, M.D., 2005. [Invited speaker]. In: Third International Congress on “Familial Mediterranean Fever and Systemic Autoinflammatory Diseases”, Bethesda, USA, 2005, Bethesda, USA.

YOUSAF, N., GOULD, D.J., AGANNA, E., HAMMOND, L., MIRAKIAN, R.M., TURNER, M.D., HITMAN, G.A., MCDERMOTT, M. and CHERNAJOVSKY, Y., 2005. Tumor necrosis factor receptor I from patients with tumor necrosis factor receptor-associated periodic syndrome interacts with wild-type tumor necrosis factor receptor I and induces ligand-independent NF-kappaB activation. Arthritis & Rheumatism, 52, pp. 2906-2916.

TURNER, M.D., 2004. Fatty acyl CoA-mediated inhibition of endoplasmic reticulum assembly. Biochimica et Biophysica Acta, 1693, pp. 1-4.

TURNER, M.D., 2004. [Invited speaker]. In: British Society for Cell Biology Annual Conference, Canterbury, 2004, Canterbury.

TURNER, M.D. and ARVAN, P., 2000. Protein traffic from the secretory pathway to the endosomal system in pancreatic beta-cells. Journal of Biological Chemistry, 275, pp. 14025-14030.

TURNER, M.D., PLUTNER, H. and BALCH, W.E., 1997. A Rab GTPase is required for homotypic assembly of the endoplasmic reticulum. Journal of Biological Chemistry, 272, pp. 13479-13483.

BLATCHFORD, D.E., HENDRY, K.A.K., TURNER, M.D., BURGOYNE, R.D. and WILDE, C.J., 1995. Vectorial secretion by constitutive and regulated pathways in mammary epithelial cells. Epithelial Cell Biology, 4, pp. 8-16.

WILDE, C.J., ADDEY, C.V.P., BURGOYNE, R.D., CLARK, A.J., HANDEL, S.E., KERR, M.A., MCCLENAGHAN, M., RENNISON, M.E., SIMONS, J.P. and TURNER, M.D., 1994. Autocrine regulation of milk protein secretion. In: K. OKAMURA, ed., Animal cell technology: basic and applied aspects. Dordrecht: Kluwer Academic Publishers.

BURGOYNE, R.D., HANDEL, S.E., SUDLOW, A.W., TURNER, M.D., KUMAR, S., SIMONS, P., BLATCHFORD, D.R. and WILDE, C.J., 1994. The secretory pathway for milk protein secretion and its regulation. In: C.J. WILDE, M. PEAKER and C.H. KNIGHT, eds., Intercellular signalling in the mammary gland. New York: Plenum Press.

TURNER, M.D., HANDEL, S.E., WILDE, C.J. and BURGOYNE, R.D., 1993. Differential effect of brefeldin A on phosphorylation of the caseins in lactating mouse mammary epithelial cells. Journal of Cell Science, 106, pp. 1221-1226.

RENNISON, M.E., KERR, M., ADDEY, C.P.V., HANDEL, S.E., TURNER, M.D., WILDE, C.J. and BURGOYNE, R.D., 1993. Inhibition of constitutive protein secretion from lactating mouse mammary epithelial cells by FIL (Feedback Inhibitor of Lactation) a secreted milk protein. Journal of Cell Science, 106, pp. 641-648.

TURNER, M.D., WILDE, C.J. and BURGOYNE, R.D., 1992. Exocytosis from permeabilized lactating mouse mammary epithelial cells: stimulation by Ca2+ and phorbol ester, but inhibition of regulated exocytosis by GTPgammaS. Biochemical Journal, 286, pp. 13-15.

TURNER, M.D., RENNISON, M.E., HANDEL, S.E., WILDE, C.J. and BURGOYNE, R.D., 1992. Proteins are secreted by both constitutive and regulated secretory pathways in lactating mouse mammary epithelial cells. Journal of Cell Biology, 117, pp. 269-278.

BURGOYNE, R.D., HANDEL, S.E., MORGAN, A., RENNISON, M.E., TURNER, M.D. and WILDE, C.J., 1991. Calcium, the cytoskeleton and calpactin (annexin II) in exocytotic secretion from adrenal chromaffin and mammary epithelial cells. Biochemical Society Transactions, 19, pp. 1085-1090.