Separating inhibitory and excitatory responses of epileptic brain to single-pulse electrical stimulation

Shirani, S., Valentin, A., Alarcon, G., Kazi, F. and Sanei, S. ORCID: 0000-0002-3437-2801, 2022. Separating inhibitory and excitatory responses of epileptic brain to single-pulse electrical stimulation. International Journal of Neural Systems. ISSN 0129-0657

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Abstract

To enable an accurate recognition of neuronal excitability in an epileptic brain for modelling or localization of epileptic zone, here the brain response to single-pulse electrical stimulation (SPES) has been decomposed into its inhibitory and excitatory components using adaptive singular spectrum analysis (SSA). The prime objective is to thoroughly investigate the nature of delayed responses (elicited between 100ms – 1s after SPES) for localization of the epileptic zone. SSA is a powerful subspace signal analysis method for separation of single channel signals into their constituent uncorrelated components. The consistency in the results for both early and late brain responses, verifies the usability of the approach.

Item Type:	Journal article
Publication Title:	International Journal of Neural Systems
Creators:	Shirani, S., Valentin, A., Alarcon, G., Kazi, F. and Sanei, S.
Publisher:	World Scientific Pub Co Pte Ltd
Date:	18 November 2022
ISSN:	0129-0657
Identifiers:	Number Type 10.1142/s0129065723500089 DOI 1620763 Other
Rights:	Electronic version of an article published in International Journal of Neural Systems (IJNS), 2022. 10.1142/S0129065723500089 © World Scientific Publishing Company https://www.worldscientific.com/worldscinet/ijns
Divisions:	Schools > School of Science and Technology
Record created by:	Laura Ward
Date Added:	22 Nov 2022 10:32
Last Modified:	18 Nov 2023 03:00
Related URLs:	Publisher
URI:	https://irep.ntu.ac.uk/id/eprint/47467

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