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STAVROU, V., ALI, M., GUDGEON, N., BISHOP, E.L., FULTON-WARD, T., TURLEY, B., HEISING, S., MOHAMED, S.H., HAIN, S., GEORGE, L., DENG, M., MCCOWAN, J., SHERIFF, L., DAVIES, S.P., MARZULLO, B., TENNANT, D.A., DOIG, C.L., BENDING, D.A., ROBERTS, E.W., LAVERY, G.G., DRUMMOND, R.A. and DIMELOE, S., 2026. Cytoplasmic NAD/H synthesis via NRK1 regulates inflammatory capacity and promotes survival of CD4+ T cells. Nature Communications. ISSN 2041-1723

CHUBANAVA, S., KARAVAEVA, I., EHRLICH, A.M., JUSTICIA, R.M., BASSE, A.L., KULIK, I., DALBRAM, E., AHWAZI, D., HEASELGRAVE, S.R., TROŠT, K., STOCKS, B., HODEK, O., RODRIGUES, R.N., HAVELUND, J.F., SCHLABS, F.L., LARSEN, S., YONAMINE, C.Y., HENRIQUEZ-OLGUÍN, C., LUDWIG, C., GIUSTARINI, D., ROSSI, R., GERHART-HINES, Z., MORITZ, T., ZIERATH, J.R., SAKAMOTO, K., JENSEN, T.E., FÆRGEMAN, N.J., LAVERY, G.G., DESHMUKH, A.S. and TREEBAK, J.T., 2025. NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging. Cell Metabolism, 37 (7), 1460-1481.e17. ISSN 1550-4131

CRASTIN, A., SHANKER, A., SAGMEISTER, M.S., TAYLOR, A., LAVERY, G.G., RAZA, K. and HARDY, R.S., 2025. Vamorolone: a novel metabolism resistant steroid that suppresses joint destruction in chronic polyarthritis with reduced systemic side effects. Rheumatology, 64 (7), pp. 4371-4381. ISSN 1462-0332

GRECH, O., RUBIO-BELTRAN, E., STANYER, E.C., LABASTIDA-RAMIREZ, A., LAVERY, G.G., HILL, L.J., HOLLAND, P.R. and SINCLAIR, A.J., 2025. Raised intracranial pressure alters cortical vascular function and cephalic allodynia. Brain, 148 (6), pp. 2163-2177. ISSN 0006-8950

HEASELGRAVE, S.R., HEISING, S., MORGAN, S.A., CARTHWRIGHT, D.M., SAGMEISTER, M., HARDY, R.S., DOIG, C.L., MORTON, N.M., TSINTZAS, K. and LAVERY, G.G., 2024. Glucocorticoid excess alters metabolic rate and substrate utilisation via 11β-HSD1. Journal of Endocrinology, 263 (2): e240205. ISSN 0022-0795

SOMMERFELD, L.C., HOLMES, A.P., YU, T.Y., O'SHEA, C., KAVANAGH, D.M., PIKE, J.M., WRIGHT, T., SYEDA, F., ALJEHANI, A., KEW, T., CARDOSO, V.R., KABIR, S.N., HEPBURN, C., MENON, P.R., BROADWAY‐STRINGER, S., O'REILLY, M., WITTEN, A., FORTMUELLER, L., LUTZ, S., KULLE, A., GKOUTOS, G.V., PAVLOVIC, D., ARLT, W., LAVERY, G.G., STEEDS, R., GEHMLICH, K., STOLL, M., KIRCHHOF, P. and FABRITZ, L., 2024. Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse. The Journal of Physiology, 602 (18), pp. 4409-4436. ISSN 0022-3751

CUOZZO, F., VILORIA, K., SHILLEH, A.H., NASTESKA, D., FRAZER-MORRIS, C., TONG, J., JIAO, Z., BOUFERSAOUI, A., MARZULLO, B., ROSOFF, D.B., SMITH, H.R., BONNER, C., KERR-CONTE, J., PATTOU, F., NANO, R., PIEMONTI, L., JOHNSON, P.R.V., SPIERS, R., ROBERTS, J., LAVERY, G.G., CLARK, A., CERESA, C.D.L., RAY, D.W., HODSON, L., DAVIES, A.P., RUTTER, G.A., OSHIMA, M., SCHARFMANN, R., MERRINS, M.J., AKERMAN, I., TENNANT, D.A., LUDWIG, C. and HODSON, D.J., 2024. LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells. Cell Reports, 43 (4): 114047. ISSN 2211-1247

GÓMEZ, C., ALIMAJSTOROVIC, Z., OTHONOS, N., WINTER, D.V., WHITE, S., LAVERY, G.G., TOMLINSON, J.W., SINCLAIR, A.J. and ODERMATT, A., 2024. Identification of a human blood biomarker of pharmacological 11β‐hydroxysteroid dehydrogenase 1 inhibition. British Journal of Pharmacology, 181 (5), pp. 698-711. ISSN 0007-1188

DINEEN, R.A., MARTIN-GRACE, J., AHMED, K.M.S., TAYLOR, A.E., SHAHEEN, F., SCHIFFER, L., GILLIGAN, L.C., LAVERY, G.G., FRIZELLE, I., GUNNESS, A., GARRAHY, A., HANNON, A.M., METHLIE, P., EYSTEIN, S.H., STEWART, P.M., TOMLINSON, J.W., HAWLEY, J.M., KEEVIL, B.G., O’REILLY, M.W., SMITH, D., MCDERMOTT, J., HEALY, M.-L., AGHA, A., PAZDERSKA, A., GIBNEY, J., BEHAN, L.-A., THOMPSON, C.J., ARLT, W. and SHERLOCK, M., 2023. Tissue glucocorticoid metabolism in adrenal insufficiency: a prospective study of dual-release hydrocortisone therapy. The Journal of Clinical Endocrinology and Metabolism, 108 (12), pp. 3178-3189. ISSN 0021-972X

QUINLAN, J.I., DHALIWAL, A., WILLIAMS, F.R., ALLEN, S.L., CHOUDHARY, S., ROWLANDS, A., BREEN, L., LAVERY, G.G., LORD, J.M., ELSHARKAWY, A.M., ARMSTRONG, M.J. and GREIG, C.A., 2023. Impaired lower limb muscle mass, quality and function in end stage liver disease: a cross‐sectional study. Experimental Physiology, 108 (8), pp. 1066-1079. ISSN 0958-0670

SUN, C., SERANOVA, E., COHEN, M.A., CHIPARA, M., ROBERTS, J., ASTUTI, D., PALHEGYI, A.M., ACHARJEE, A., SEDLACKOVA, L., KATAURA, T., OTTEN, E.G., PANDA, P.K., LARA-REYNA, S., KORSGEN, M.E., KAUFFMAN, K.J., HUERTA-URIBE, A., ZATYKA, M., SILVA, L.F.S.E., TORRESI, J., ZHANG, S., HUGHES, G.W., WARD, C., KUECHLER, E.R., CARTWRIGHT, D., TRUSHIN, S., TRUSHINA, E., SAHAY, G., BUGANIM, Y., LAVERY, G.G., GSPONER, J., ANDERSON, D.G., FRICKEL, E.-M., ROSENSTOCK, T.R., BARRETT, T., MADDOCKS, O.D.K., TENNANT, D.A., WANG, H., JAENISCH, R., KOROLCHUK, V.I. and SARKAR, S., 2023. NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency. Cell Reports, 42 (5): 112372. ISSN 2211-1247

PATRICK, K., TIAN, X., CARTWRIGHT, D., HEISING, S., GLOVER, M.S., NORTHALL, E.N., CAZARES, L., HESS, S., BAKER, D., CHURCH, C., DAVIES, G., LAVERY, G. and NAYLOR, A.J., 2023. Sex-specific effects of CD248 on metabolism and the adipose tissue lipidome. PLOS ONE, 18 (4): e0284012. ISSN 1932-6203

TAN, A., YOUNIS, A.Z., EVANS, A., CREIGHTON, J.V., COVENEY, C., BOOCOCK, D.J., SALE, C., LAVERY, G.G., COUTTS, A.S. and DOIG, C.L., 2023. PARP1 mediated PARylation contributes to myogenic progression and glucocorticoid transcriptional response. Cell Death Discovery, 9: 133. ISSN 2058-7716

WEBSTER, J.M., WAAIJENBERG, K., VAN DE WORP, W.R.P.H., KELDERS, M.C.J.M., LAMBRICHTS, S., MARTIN, C., VERHAEGEN, F., VAN DER HEYDEN, B., SMITH, C., LAVERY, G.G., SCHOLS, A.M.W.J., HARDY, R.S. and LANGEN, R.C.J., 2023. 11β-HSD1 determines the extent of muscle atrophy in a model of acute exacerbation of COPD. AJP - Lung Cellular and Molecular Physiology, 324 (4), L400-L412. ISSN 1040-0605

YOUNIS, A.Z., LAVERY, G.G., CHRISTIAN, M. and DOIG, C.L., 2023. Rapid isolation of respiring skeletal muscle mitochondria using nitrogen cavitation. Frontiers in Physiology, 14: 1114595. ISSN 1664-042X

MERK, V.M., PHAN, T.S., WIEDMANN, A., HARDY, R.S., LAVERY, G.G. and BRUNNER, T., 2023. Local glucocorticoid synthesis regulates house dust mite-induced airway hypersensitivity in mice. Frontiers in Immunology, 14: 1252874. ISSN 1664-3224

MORGAN, S.A., GATHERCOLE, L.L., HASSAN-SMITH, Z.K., TOMLINSON, J., STEWART, P.M. and LAVERY, G.G., 2022. 11β-HSD1 contributes to age-related metabolic decline in male mice. Journal of Endocrinology, 255 (3), pp. 117-129. ISSN 0022-0795

WESTGATE, C.S.J., MARKEY, K., MITCHELL, J.L., YIANGOU, A., SINGHAL, R., STEWART, P., TOMLINSON, J.W., LAVERY, G.G., MOLLAN, S.P. and SINCLAIR, A.J., 2022. Increased systemic and adipose 11β-HSD1 activity in idiopathic intracranial hypertension. European Journal of Endocrinology, 187 (2), pp. 323-333. ISSN 0804-4643

YIANGOU, A., MITCHELL, J.L., NICHOLLS, M., CHONG, Y.J., VIJAY, V., WAKERLEY, B.R., LAVERY, G.G., TAHRANI, A.A., MOLLAN, S.P. and SINCLAIR, A.J., 2022. Obstructive sleep apnoea in women with idiopathic intracranial hypertension: a sub-study of the idiopathic intracranial hypertension weight randomised controlled trial (IIH: WT). Journal of Neurology, 269 (4), pp. 1945-1956. ISSN 0340-5354

WESTBROOK, R.L., BRIDGES, E., ROBERTS, J., ESCRIBANO-GONZALEZ, C., EALES, K.L., VETTORE, L.A., WALKER, P.D., VERA-SIGUENZA, E., RANA, H., CUOZZO, F., ESKLA, K.-L., VELLAMA, H., SHAABAN, A., NIXON, C., LUUK, H., LAVERY, G.G., HODSON, D.J., HARRIS, A.L. and TENNANT, D.A., 2022. Proline synthesis through PYCR1 is required to support cancer cell proliferation and survival in oxygen-limiting conditions. Cell Reports, 38 (5): 110320. ISSN 2211-1247

MORGAN, S.A., BERRYMAN, D.E., LIST, E.O., LAVERY, G.G., STEWART, P.M. and KOPCHICK, J.J., 2022. Regulation of 11β-HSD1 by GH/IGF-1 in key metabolic tissues may contribute to metabolic disease in GH deficient patients. Growth Hormone and IGF Research, 62: 101440. ISSN 1096-6374

CARTWRIGHT, D.M., OAKEY, L.A., FLETCHER, R.S., DOIG, C.L., HEISING, S., LARNER, D.P., NASTESKA, D., BERRY, C.E., HEASELGRAVE, S.R., LUDWIG, C., HODSON, D.J., LAVERY, G.G. and GARTEN, A., 2021. Nicotinamide riboside has minimal impact on energy metabolism in mouse models of mild obesity. Journal of Endocrinology, 251 (1), pp. 111-123. ISSN 0022-0795

NASTESKA, D., CUOZZO, F., VILORIA, K., JOHNSON, E.M., THAKKER, A., BANY BAKAR, R., WESTBROOK, R.L., BARLOW, J.P., HOANG, M., JOSEPH, J.W., LAVERY, G.G., AKERMAN, I., CANTLEY, J., HODSON, L., TENNANT, D.A. and HODSON, D.J., 2021. Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice. JCI Insight, 6 (16): e140288. ISSN 2379-3708

WEINGARTNER, M., STÜCHELI, S., KRATSCHMAR, D.V., BIRK, J., KLUSONOVA, P., CHAPMAN, K.E., LAVERY, G.G. and ODERMATT, A., 2021. The ratio of ursodeoxycholyltaurine to 7‐oxolithocholyltaurine serves as a biomarker of decreased 11β‐hydroxysteroid dehydrogenase 1 activity in mouse. British Journal of Pharmacology, 178 (16), pp. 3309-3326. ISSN 0007-1188

WEBSTER, J.M., SAGMEISTER, M.S., FENTON, C.G., SEABRIGHT, A.P., LAI, Y.-C., JONES, S.W., FILER, A., COOPER, M.S., LAVERY, G.G., RAZA, K., LANGEN, R. and HARDY, R.S., 2021. Global Deletion of 11β-HSD1 prevents muscle wasting associated with glucocorticoid therapy in polyarthritis. International Journal of Molecular Sciences, 22 (15): 7828. ISSN 1661-6596

ALLEN, S.L., MARSHALL, R.N., EDWARDS, S.J., LORD, J.M., LAVERY, G.G. and BREEN, L., 2021. The effect of young and old ex vivo human serum on cellular protein synthesis and growth in an in vitro model of aging. American Journal of Physiology-Cell Physiology, 321 (1), C26-C37. ISSN 0363-6143

MOLLAN, S.P., MITCHELL, J.L., OTTRIDGE, R.S., AGUIAR, M., YIANGOU, A., ALIMAJSTOROVIC, Z., CARTWRIGHT, D.M., GRECH, O., LAVERY, G.G., WESTGATE, C.S.J., VIJAY, V., SCOTTON, W., WAKERLEY, B.R., MATTHEWS, T.D., ANSONS, A., HICKMAN, S.J., BENZIMRA, J., RICK, C., SINGHAL, R., TAHRANI, A.A., BROCK, K., FREW, E. and SINCLAIR, A.J., 2021. Effectiveness of bariatric surgery vs community weight management intervention for the treatment of idiopathic intracranial hypertension: a randomized clinical trial. JAMA Neurology, 78 (6), pp. 678-686. ISSN 2168-6149

KIM, B.J., LEE, N.R., LEE, C.H., LEE, Y.B., CHOE, S.J., LEE, S., HWANG, H.J., KIM, E., LAVERY, G.G., SHIN, K.-O., PARK, K. and CHOI, E.H., 2021. Increased expression of 11β-hydroxysteroid dehydrogenase type 1 contributes to epidermal permeability barrier dysfunction in aged skin. International Journal of Molecular Sciences, 22 (11): 5750. ISSN 1661-6596

WESTGATE, C.S.J., BOTFIELD, H.F., ALIMAJSTOROVIC, Z., YIANGOU, A., WALSH, M., SMITH, G., SINGHAL, R., MITCHELL, J.L., GRECH, O., MARKEY, K.A., HEBENSTREIT, D., TENNANT, D.A., TOMLINSON, J.W., MOLLAN, S.P., LUDWIG, C., AKERMAN, I., LAVERY, G.G. and SINCLAIR, A.J., 2021. Systemic and adipocyte transcriptional and metabolic dysregulation in idiopathic intracranial hypertension. JCI Insight, 6 (10): e145346. ISSN 2379-3708

GRECH, O., MOLLAN, S.P., WAKERLEY, B.R., FULTON, D., LAVERY, G.G. and SINCLAIR, A.J., 2021. The role of metabolism in migraine pathophysiology and susceptibility. Life, 11 (5): 415. ISSN 2075-1729

TANNOUS, C., DELOUX, R., KAROUI, A., MOUGENOT, N., BURKIN, D., BLANC, J., COLETTI, D., LAVERY, G., LI, Z. and MERICSKAY, M., 2021. NMRK2 gene is upregulated in dilated cardiomyopathy and required for cardiac function and NAD levels during aging. International Journal of Molecular Sciences, 22 (7): 3534. ISSN 1661-6596

STOCKS, B., ASHCROFT, S.P., JOANISSE, S., DANSEREAU, L.C., KOAY, Y.C., ELHASSAN, Y.S., LAVERY, G.G., QUEK, L., O'SULLIVAN, J.F., PHILP, A.M., WALLIS, G.A. and PHILP, A., 2021. Nicotinamide riboside supplementation does not alter whole‐body or skeletal muscle metabolic responses to a single bout of endurance exercise. The Journal of Physiology, 599 (5), pp. 1513-1531. ISSN 0022-3751

ALLEN, S.L., QUINLAN, J.I., DHALIWAL, A., ARMSTRONG, M.J., ELSHARKAWY, A.M., GREIG, C.A., LORD, J.M., LAVERY, G.G. and BREEN, L., 2021. Sarcopenia in chronic liver disease: mechanisms and countermeasures. American Journal of Physiology - Gastrointestinal and Liver Physiology, 320 (3), G241-G257. ISSN 0193-1857

FENTON, C., MARTIN, C., JONES, R., CROFT, A., CAMPOS, J., NAYLOR, A.J., TAYLOR, A.E., CHIMEN, M., COOPER, M., LAVERY, G.G., RAZA, K. and HARDY, R.S., 2021. Local steroid activation is a critical mediator of the anti-inflammatory actions of therapeutic glucocorticoids. Annals of the Rheumatic Diseases, 80 (2), pp. 250-260. ISSN 0003-4967

ARMITAGE, E.G., BARNES, A., PATRICK, K., BECHAR, J., HARRISON, M.J., LAVERY, G.G., RAINGER, G.E., BUCKLEY, C.D., LOFTUS, N.J., WILSON, I.D. and NAYLOR, A.J., 2021. Metabolic consequences for mice lacking endosialin: LC–MS/MS-based metabolic phenotyping of serum from C56Bl/6J control and CD248 knock‐out mice. Metabolomics, 17 (2). ISSN 1573-3882

SINTON, M.C., MESEGUER-RIPOLLES, J., LUCENDO-VILLARIN, B., WERNIG-ZORC, S., THOMSON, J.P., CARTER, R.N., LYALL, M.J., WALKER, P.D., THAKKER, A., MEEHAN, R.R., LAVERY, G.G., MORTON, N.M., LUDWIG, C., TENNANT, D.A., HAY, D.C. and DRAKE, A.J., 2021. A human pluripotent stem cell model for the analysis of metabolic dysfunction in hepatic steatosis. iScience, 24 (1): 101931. ISSN 2589-0042

HARDY, R.S., BOTFIELD, H., MARKEY, K., MITCHELL, J.L., ALIMAJSTOROVIC, Z., WESTGATE, C.S.J., SAGMEISTER, M., FAIRCLOUGH, R.J., OTTRIDGE, R.S., YIANGOU, A., STORBECK, K.-H.H., TAYLOR, A.E., GILLIGAN, L.C., ARLT, W., STEWART, P.M., TOMLINSON, J.W., MOLLAN, S.P., LAVERY, G.G. and SINCLAIR, A.J., 2021. 11βHSD1 inhibition with AZD4017 improves lipid profiles and lean muscle mass in idiopathic intracranial hypertension. The Journal of Clinical Endocrinology and Metabolism, 106 (1), pp. 174-187. ISSN 0021-972X

YIANGOU, A., MITCHELL, J.L., FISHER, C., EDWARDS, J., VIJAY, V., ALIMAJSTOROVIC, Z., GRECH, O., LAVERY, G.G., MOLLAN, S.P. and SINCLAIR, A.J., 2021. Erenumab for headaches in idiopathic intracranial hypertension: a prospective open‐label evaluation. Headache: The Journal of Head and Face Pain, 61 (1), pp. 157-169. ISSN 0017-8748

MAHIDA, R.Y., SCOTT, A., PAREKH, D., LUGG, S.T., HARDY, R.S., LAVERY, G.G., MATTHAY, M.A., NAIDU, B., PERKINS, G.D. and THICKETT, D.R., 2021. Acute respiratory distress syndrome is associated with impaired alveolar macrophage efferocytosis. European Respiratory Journal, 58 (3): 2100829. ISSN 0903-1936

DHALIWAL, A., WILLIAMS, F.R., QUINLAN, J.I., ALLEN, S.L., GREIG, C., FILER, A., RAZA, K., GHOSH, S., LAVERY, G.G., NEWSOME, P.N., CHOUDHARY, S., BREEN, L., ARMSTRONG, M.J., ELSHARKAWY, A.M. and LORD, J.M., 2021. Evaluation of the mechanisms of sarcopenia in chronic inflammatory disease: protocol for a prospective cohort study. Skeletal Muscle, 11: 27. ISSN 2044-5040

MOLLAN, S.P., WAKERLEY, B.R., ALIMAJSTOROVIC, Z., MITCHELL, J., OTTRIDGE, R., YIANGOU, A., THALLER, M., GUPTA, A., GRECH, O., LAVERY, G., BROCK, K. and SINCLAIR, A.J., 2021. Intracranial pressure directly predicts headache morbidity in idiopathic intracranial hypertension. The Journal of Headache and Pain, 22: 118. ISSN 1129-2369

DOIG, C.L. and LAVERY, G.G., 2016. PARP inhibitors: staying on target? Cell Chemical Biology, 23 (12), pp. 1442-1443. ISSN 2451-9456

DOIG, C.L., BASHIR, J., ZIELINSKA, A.E., COOPER, M.S., STEWART, P.M. and LAVERY, G.G., 2014. TNFα-mediated Hsd11b1 binding of NF-κB p65 is associated with suppression of 11β-HSD1 in muscle. Journal of Endocrinology, 220 (3), pp. 389-396. ISSN 0022-0795