Items where Author is "Hargreaves, AJ"

Journal article

ABEDIN, N., WAGNER, S., KHALKAR, Y.S., JOHNSON, Z., EGBOWON, B.F., HARGREAVES, A.J., FITZPATRICK, A.J., MILES, A.K. and DAFHNIS-CALAS, F., 2025. Protein profile of the Escherichia coli strain, BW25113, exposed to two novel iron-halide compounds: Fe(Hampy)2Cl4 and Fe(Hampy)2Br4. Access Microbiology, 7 (1): 000783.v4. ISSN 2516-8290

EGBOWON, B.F., FORNARI, E., PALLY, J.M., HARGREAVES, A.J., STEVENS, B., MCGINNITY, T.M. and PIERSCIONEK, B.K., 2023. Retinal pigment epithelial cells can be cultured on fluocinolone acetonide treated nanofibrous scaffold. Materials and Design, 232: 112152. ISSN 0264-1275

LAM, A., OHAYON, E., HOGBERG, H.T., SHAHBAZ, M.A., CLERBAUX, L.-A., BAL-PRICE, A., COECKE, S., CONCHA, R., DE BERNARDI, F., EDROSA, E., HARGREAVES, A.J., KANNINEN, K.M., MUNOZ, A., PISTOLLATO, F., SARAVANAN, S., GARCIA-REYERO, N., WITTWEHR, C. and SACHANA, M., 2022. The adverse outcome pathway framework applied to neurological symptoms of COVID-19. Cells, 11 (21): 3411. ISSN 2073-4409

WEIR, N., STEVENS, B., WAGNER, S., MILES, A., BALL, G., HOWARD, C., CHEMMARAPPALLY, J., MCGINNITY, M., HARGREAVES, A.J. and TINSLEY, C., 2022. Aligned poly-L-lactic acid nanofibers induce self-assembly of primary cortical neurons into 3D cell clusters. ACS Biomaterials Science and Engineering, 8 (2), pp. 765-776. ISSN 2373-9878

ALMAMI, I.S., ALDUBAYAN, M.A., FELEMBAN, S.G., ALYAMANI, N., HOWDEN, R., ROBINSON, A.J., PEARSON, T.D.Z., BOOCOCK, D., ALGARNI, A.S., GARNER, A.C., GRIFFIN, M., BONNER, P.L.R. and HARGREAVES, A.J., 2020. Neurite outgrowth inhibitory levels of organophosphates induce tissue transglutaminase activity in differentiating N2a cells: evidence for covalent adduct formation. Archives of Toxicology, 94 (11), pp. 3861-3875. ISSN 0340-5761

ABEDIN, N., HAMED A ALSHEHRI, A., ALMUGHRBI, A.M.A., MOORE, O., ALYZA, S., RUSBRIDGE, E.K., MASOOD, N., EGBOWON, B.F., HARGREAVES, A.J., DAFHNIS-CALAS, F. and FITZPATRICK, A.J., 2020. Expanding the family of tetrahalide iron complexes: synthesis, structure and biological applications. Polyhedron: 114755. ISSN 0277-5387

CHEMMARAPPALLY, J.M., PEGRAM, H.C.N., ABEYWICKRAMA, N., FORNARI, E., HARGREAVES, A.J., DE GIROLAMO, L.A. and STEVENS, B., 2020. A co-culture nanofibre scaffold model of neural cell degeneration in relevance to Parkinson’s disease. Scientific Reports, 10: 2767. ISSN 2045-2322

ALGARNI, A.S., HARGREAVES, A.J. and DICKENSON, J.M., 2018. Activation of transglutaminase 2 by nerve growth factor in differentiating neuroblastoma cells: a role in cell survival and neurite outgrowth. European Journal of Pharmacology, 820, pp. 113-129. ISSN 0014-2999

VYAS, F.S., NELSON, C.P., FREEMAN, F., BOOCOCK, D.J., HARGREAVES, A.J. and DICKENSON, J.M., 2017. β2-adrenoceptor-induced modulation of transglutaminase 2 transamidase activity in cardiomyoblasts. European Journal of Pharmacology. ISSN 0014-2999

ALGARNI, A.S., HARGREAVES, A.J. and DICKENSON, J.M., 2017. Role of transglutaminase 2 in PAC1 receptor mediated protection against hypoxia-induced cell death and neurite outgrowth in differentiating N2a neuroblastoma cells. Biochemical Pharmacology, 128, pp. 55-73. ISSN 0006-2952

SINDI, R.A., HARRIS, W., ARNOTT, G., FLASKOS, J., LLOYD MILLS, C. and HARGREAVES, A.J., 2016. Chlorpyrifos- and chlorpyrifos oxon-induced neurite retraction in pre-differentiated N2a cells is associated with transient hyperphosphorylation of neurofilament heavy chain and ERK 1/2. Toxicology and Applied Pharmacology, 308, pp. 20-31. ISSN 0041-008X

VYAS, F.S., HARGREAVES, A.J., BONNER, P.L.R., BOOCOCK, D.J., COVENEY, C. and DICKENSON, J.M., 2016. A1 adenosine receptor-induced phosphorylation and modulation of transglutaminase 2 activity in H9c2 cells: a role in cell survival. Biochemical Pharmacology, 107, pp. 41-58. ISSN 0006-2952

EGBOWON, B.F., HARRIS, W., ARNOTT, G., MILLS, C.L. and HARGREAVES, A.J., 2016. Sub-lethal concentrations of CdCl2 disrupt cell migration and cytoskeletal proteins in cultured mouse TM4 Sertoli cells. Toxicology in Vitro, 32, pp. 154-165. ISSN 0887-2333

DAUBNEY, J., BONNER, P.L., HARGREAVES, A.J. and DICKENSON, J.M., 2015. Cardioprotective and cardiotoxic effects of Quercetin and two of its in vivo metabolites on differentiated H9c2 cardiomyocytes. Basic & Clinical Pharmacology & Toxicology, 116 (2), pp. 96-109. ISSN 1742-7835

FELEMBAN, S.G., GARNER, A.C., SMIDA, F.A., BOOCOCK, D.J., HARGREAVES, A.J. and DICKENSON, J.M., 2015. Phenyl Saligenin Phosphate Induced Caspase-3 and c-Jun N-Terminal Kinase Activation in Cardiomyocyte-Like Cells. Chemical Research in Toxicology, 28 (11), pp. 2179-2191. ISSN 0893-228X

ALMAMI, I., DICKENSON, J.M., HARGREAVES, A.J. and BONNER, P.L.R., 2014. Modulation of transglutaminase 2 activity in H9c2 cells by PKC and PKA signalling: a role for transglutaminase 2 in cytoprotection. British Journal of Pharmacology, 171 (16), pp. 3946-3960. ISSN 00071188

SACHANA, M., SIDIROPOULOU, E., FLASKOS, J., HARRIS, W., ROBINSON, A.J., WOLDEHIWET, Z. and HARGREAVES, A.J., 2014. Diazoxon disrupts the expression and distribution of βIII-tubulin and MAP 1B in differentiating N2a cells. Basic & Clinical Pharmacology & Toxicology, 114 (6), pp. 490-496. ISSN 1742-7835

BURTÉ, F., DE GIROLAMO, L.A., HARGREAVES, A.J. and BILLETT, E.E., 2011. Alterations in the mitochondrial proteome of neuroblastoma cells 2 in response to complex 1 inhibition. Journal of Proteome Research, 10 (4). ISSN 1535-3893

MUÑOZ, D., BONNER, P.L.R. and HARGREAVES, A.J., 2010. Effects of chlorpyrifos on transglutaminase activity in differentiating rat C6 glioma cells. Toxicology in Vitro, 24 (8), pp. 2104-2107.

MUÑOZ, D., BONNER, P.L.R. and HARGREAVES, A.J., 2010. Effects of chlorpyrifos on transglutaminase activity in differentiating rat C6 glioma cells. Toxicology in Vitro, 24 (8), pp. 2104-2107. ISSN 0887-2333

DI, S., DEL, D., VERDERIO, E., HARGREAVES, A.J., SCARPELLINI, A., CAI, G., CRESTI, M., FALERI, C., IORIO, R.A., HIROSE, S., FURUTANI, Y., COUTTS, I.G., GRIFFIN, M., BONNER, P.L. and SERAFINI-FRACASSINI, D., 2010. An extracellular transglutaminase is required for apple pollen tube growth. Biochemical Journal, 429, pp. 261-271.

SIDIROPOULOU, E., SACHANA, M., FLASKOS, J., HARRIS, W., HARGREAVES, A.J. and WOLDEHIWET, Z., 2009. Diazinon oxon interferes with differentiation of rat C6 glioma cells. Toxicology in Vitro, 23 (8), pp. 1548-1552. ISSN 0887-2333

HARRIS, W., MUNOZ, D., BONNER, P.L.R. and HARGREAVES, A.J., 2009. Effects of phenyl saligenin phosphate on cell viability and transglutaminase activity in N2a neuroblastoma and HepG2 hepatoma cell lines. Toxicology in Vitro, 23 (8), pp. 1559-1563. ISSN 0887-2333

HARRIS, W., SACHANA, M., FLASKOS, J. and HARGREAVES, A.J., 2009. Neuroprotection from diazinon-induced toxicity in differentiating murine N2a neuroblastoma cells. Neurotoxicology, 30 (6), pp. 958-964. ISSN 0161-813X

HARRIS, W., SACHANA, M., FLASKOS, J. and HARGREAVES, A.J., 2009. Proteomic analysis of differentiating neuroblastoma cells treated with sub-lethal neurite inhibitory concentrations of diazinon: identification of novel biomarkers of effect. Toxicology and Applied Pharmacology, 240 (2), pp. 159-165. ISSN 0041-008X

SACHANA, M., FLASKOS, J., SIDIROPOULOU, E., YAVARI, C.A. and HARGREAVES, A.J., 2008. Inhibition of extension outgrowth in differentiating rat C6 glioma cells by chlorpyrifos and chlorpyrifos oxon: effects on microtubule proteins. Toxicology in Vitro, 22 (5), pp. 1387-1391. ISSN 0887-2333

LAWTON, M., IQBAL, M., KONTOVRAKI, M., LLOYD MILLS, C. and HARGREAVES, A.J., 2007. Reduced tubulin tyrosination as an early marker of mercury toxicity in differentiating N2a cells. Toxicology in Vitro, 21 (7), pp. 1258-1261. ISSN 0887-2333

FLASKOS, J., HARRIS, W., SACHANA, M., MUNOZ, D., TACK, J. and HARGREAVES, A.J., 2007. The effects of diazinon and cypermethrin on the differentiation of neuronal and glial cell lines. Toxicology and Applied Pharmacology, 219, pp. 172-180. ISSN 0041-008X

FLASKOS, J., SACHANA, M., PEN, M., HARRIS, W.C. and HARGREAVES, A.J., 2006. Effects of phenyl saligenin phosphate on phosphorylation of pig brain tubulin in vitro. Environmental Toxicology and Pharmacology, 22 (1), pp. 70-74. ISSN 1382-6689

HOWDEN, R., BONNER, P.L.R., GRIFFIN, M. and HARGREAVES, A.J., 2006. Inhibition of neurite outgrowth by phenyl saligenin phosphate: effects on neural transglutaminase activity. FEBS Journal, 273, p. 244. ISSN 1742-464X

HARGREAVES, A.J., FOWLER, M.J., SACHANA, M., FLASKOS, J., BOUNTOURI, M., COUTTS, I.C., GLYNN, P., HARRIS, W. and MCLEAN, W.G., 2006. Inhibition of neurite outgrowth in differentiating mouse N2a neuroblastoma cells by phenyl saligenin phosphate: Effects on MAP kinase (ERK 1/2) activation, neurofilament heavy chain phosphorylation and neuropathy target esterase activity. Biochemical Pharmacology, 71 (8), pp. 1240-1247. ISSN 0006-2952

HARGREAVES, A.J., FOWLER, M.J., SACHANA, M., FLASKOS, J., BOUNTOURI, M., COUTTS, I.C., GLYNN, P., HARRIS, W. and MCLEAN, W.G., 2006. Inhibition of neurite outgrowth in differentiating mouse N2a neuroblastoma cells by phenyl saligenin phosphate: Effects on MAP kinase (ERK 1/2) activation, neurofilament heavy chain phosphorylation and neuropathy target esterase activity. Biochemical Pharmacology, 71 (8), pp. 1240-1247. ISSN 0006-2952

TRIGWELL, S., HOWDEN, R., LYNCH, P.T., HARGREAVES, A.J. and BONNER, P.L.R., 2006. Molecular markers in the cryopreservation of olive and garlic tissue. FEBS Journal, 273, p. 353. ISSN 1742-464X

SACHANA, M., FLASKOS, J. and HARGREAVES, A.J., 2005. Effects of chlorpyrifos and chlorpyrifos-methyl on cytoskeletal proteins and MAP kinase (ERK 1/2) activation in N2a cells. Toxicology, 213 (3), pp. 263-264. ISSN 0300-483X

SACHANA, M., FLASKOS, J. and HARGREAVES, A.J., 2005. Effects of chlorpyrifos and chlorpyrifos-methyl on the outgrowth of axon-like processes, tubulin, and GAP-43 in N2a cells. Toxicology Mechanisms and Methods, 15 (6), pp. 405-410. ISSN 1537-6524

HARGREAVES, A.J., HARRIS, W.C., TACK, J., SACHANA, M. and FLASKOS, J., 2005. Effects of diazinon and cypermethrin on differentiating N2a and C6 cells. FEBS Journal, 272, p. 439. ISSN 1742-464X

HOWDEN, R., BONNER, P.L.R., GRIFFIN, M. and HARGREAVES, A.J., 2005. Neural transglutaminase as a potential target for organophosphate toxicity. FEBS Journal, 272, pp. 410-411. ISSN 1742-464X

LAWTON, M.D., LLOYD MILLS, C. and HARGREAVES, A.J., 2005. The effects of organic mercury compounds on differentiating neuronal and glial cells. FEBS Journal, 272, p. 442. ISSN 1742-464X

CORTEZ, J., BONNER, P.L.R., GRIFFIN, M., HARRIS, W., LYNCH, P.T. and HARGREAVES, A.J., 2004. Application of transglutaminases in the modification of wool textiles. Enzyme and Microbial Technology, 34 (1), pp. 64-72. ISSN 0141-0229

HARRIS, W., LYNCH, P.T., HARGREAVES, A.J. and BONNER, P.L.R., 2004. Cryopreservation of Helianthus tuberosus cell suspension cultures: The effect of preculture treatments on cytoskeletal proteins and transglutaminase activity. Cryoletters, 25 (3), pp. 213-217. ISSN 0143-2044

SACHANA, M., FLASKOS, J. and HARGREAVES, A.J., 2004. Effects of chlorpyrifos on the neurofilament network and MAP kinase (ERK 1/2) activation in N2a cells. Toxicology and Applied Pharmacology, 197 (3), p. 322. ISSN 0041-008X

TRIGWELL, S.M., LYNCH, P.T., GRIFFIN, M., HARGREAVES, A.J. and BONNER, P.L.R., 2004. An improved colorimetric assay for the measurement of transglutaminase (type II) -(γ-glutamyl) lysine cross-linking activity. Analytical Biochemistry, 330 (1), pp. 164-166. ISSN 0003-2697

TRIGWELL, S.M., LYNCH, P.T., GRIFFIN, M., HARGREAVES, A.J. and BONNER, P.L.R., 2004. An improved colorimetric assay for the measurement of transglutaminase (type II) epsilon-(gamma-glutamyl) lysine cross-linking activity. Analytical Biochemistry, 330 (1), pp. 164-166. ISSN 0003-2697

SACHANA, M., FLASKOS, J., ALEXAKI, E. and HARGREAVES, A.J., 2003. Inhibition of neurite outgrowth in N2a cells by leptophos and carbaryl: effects on neurofilament heavy chain, GAP-43 and HSP-70. Toxicology in Vitro, 17 (1), pp. 115-120. ISSN 0887-2333

FOWLER, M.J., FLASKOS, J., MCLEAN, W.G. and HARGREAVES, A.J., 2001. Effects of neuropathic and non-neuropathic isomers of tricresyl phosphate and their microsomal activation on the production of axon-like processes by differentiating mouse N2a neuroblastoma cells. Journal of Neurochemistry, 76 (3), pp. 671-678. ISSN 0022-3042

DE, G., HARGREAVES, A.J. and BILLETT, E.E., 2001. Protection from MPTP-induced neurotoxicity in differentiating mouse N2a neuroblastoma cells. Journal of Neurochemistry, 76 (3), pp. 650-660. ISSN 0022-3042

HILTON, C.L., MACKEY, B.M., HARGREAVES, A.J. and FORSYTHE, S.J., 2001. The recovery of Arcobacter butzleri NCTC 12481 from various temperature treatments. Journal of Applied Microbiology, 91 (5), pp. 929-932. ISSN 1364-5072

SACHANA, M., FLASKOS, J., ALEXAKI, E., GLYNN, P. and HARGREAVES, A.J., 2001. The toxicity of chlorpyrifos towards differentiating mouse N2a neuroblastoma cells. Toxicology in Vitro, 15 (4), pp. 369-372. ISSN 0887-2333

DE, G., BILLETT, E.E. and HARGREAVES, A.J., 2000. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on differentiating mouse N2a neuroblastoma cells. Journal of Neurochemistry, 75 (1), pp. 133-140. ISSN 0022-3042

FLASKOS, J., FOWLER, M.J., TEURTRIE, C. and HARGREAVES, A.J., 1999. The effects of carbaryl and trichlorphon on differentiating mouse N2a neuroblastoma cells. Toxicology Letters, 110, pp. 79-84. ISSN 0378-4274

FLASKOS, J., MCLEAN, W.G., FOWLER, M.J. and HARGREAVES, A.J., 1998. Tricresyl phosphate inhibits the formation of axon-like processes and disrupts neurofilaments in cultured mouse N2a and rat PC12 cells. Neuroscience Letters, 242 (2), pp. 101-104. ISSN 0304-3940

DE, G. and HARGREAVES, A.J., 1997. Axon outgrowth and neurofilament protein expression in mouse neuroblastoma cells exposed to the neurotoxin MPTP. Biochemical Society Transactions, 25 (4). ISSN 0300-5127

FOWLER, M.J., MCLEAN, G., FLASKOS, J. and HARGREAVES, A.J., 1997. The effects of tricresyl phosphate on axon outgrowth and neurofilament levels in mouse N2a neuroblastoma cells. Biochemical Society Transactions, 25 (4). ISSN 0300-5127

HARGREAVES, A.J., GLAZIER, A.P., FLASKOS, J., MULLINS, F.H. and MCLEAN, W.G., 1994. The Disruption of Brain Microtubules In-Vitro by the Phospholipase Inhibitor P-Bromophenacyl Bromide. Biochemical Pharmacology, 47 (7), pp. 1137-1143. ISSN 0006-2952

FLASKOS, J., MCLEAN, W.G. and HARGREAVES, A.J., 1994. The Toxicity of Organophosphate Compounds Towards Cultured Pc12 Cells. Toxicology Letters, 70 (1), pp. 71-76. ISSN 0378-4274

MULLINS, F.H., HARGREAVES, A.J., LI, J.Y., DAHLSTROM, A. and MCLEAN, W.G., 1994. Tyrosination State of Alpha-Tubulin in Regenerating Peripheral-Nerve. Journal of Neurochemistry, 62 (1), pp. 227-234. ISSN 0022-3042

PEKINER, C., CULLUM, N.A., HUGHES, J.N., HARGREAVES, A.J., MAHON, J., CASSON, I.F. and MCLEAN, W.G., 1993. Glycation of Brain Actin in Experimental Diabetes. Journal of Neurochemistry, 61 (2), pp. 436-442. ISSN 0022-3042

HARGREAVES, A.J. and MCLEAN, W.G., 1993. Subcellular-Distribution and Immunological Detection of Retrograde Axonally Transported Proteins in Acrylamide and Diabetic Neuropathies. Neuroscience Letters, 163 (2), pp. 201-204. ISSN 0304-3940

HARGREAVES, A.J. and MCLEAN, W.G., 1991. Biochemical Subfractionation of Retrogradely Transported Proteins from Rat Sciatic-Nerve. Biochemical Society Transactions, 19 (2). ISSN 0300-5127

FLASKOS, J., MCLEAN, W.G. and HARGREAVES, A.J., 1991. The Effects of P-Bromophenacyl Bromide on Brain Microtubule Assembly Invitro. Biochemical Society Transactions, 19 (2). ISSN 0300-5127

HARGREAVES, A.J., FLASKOS, J., GLAZIER, A.P. and MCLEAN, W.G., 1991. Inhibition by Para-Bromophenacyl Bromide of Microtubule Assembly Invitro. Biochemical Society Transactions, 19 (4), pp. 1140-1143. ISSN 0300-5127

MULLINS, F.H., HARGREAVES, A.J. and MCLEAN, W.G., 1991. Tubulin - Tyrosine Ligase Activity in Regenerating Peripheral-Nerve. Biochemical Society Transactions, 19 (4), pp. 1143-1146. ISSN 0300-5127

HARGREAVES, A.J. and MCLEAN, W.G., 1988. The Characterization of Phospholipids Associated with Microtubules, Purified Tubulin and Microtubule Associated Proteins Invitro. International Journal of Biochemistry, 20 (10). ISSN 0020-711X

Authored book

BONNER, P.L.R. and HARGREAVES, A.J., 2010. Basic bioscience laboratory techniques: a pocket guide. Chichester: Wiley-Blackwell. ISBN 9780470743096